⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168087 | 0.96 | TSHR (0.33) | — | |
| SCHEMBL437421 | 0.96 | TSHR (0.33) | — | |
| SCHEMBL4167437 | 0.96 | TSHR (0.33) | — | |
| SCHEMBL5051935 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL9148805 | 0.69 | — | — | |
| SCHEMBL3714910 | 0.69 | — | — | |
| SCHEMBL20104747 | 0.69 | TSHR (0.31) | — | |
| Hydrochloric Acid SCHEMBL4048738 | 0.67 | — | — | |
| SCHEMBL8860048 | 0.65 | — | — | |
| SCHEMBL61974 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105256-A1 | PRODRUGS OF ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP. (CA) | 2009-04-23 | — | — | US | claimed |
| JP-2007531766-A | — | — | 2007-11-08 | — | — | JP | claimed |
| EP-1729815-A2 | PEGYLATED ION CHANNEL MODULATING COMPOUNDS | Cardiome Pharma Corp. (CA) | 2006-12-13 | — | — | EP | claimed |
| WO-2005113011-A2 | PRODRUGS OF ION CHANNEL MODULATING COMPOUNDS AND USES THEREOF | CARDIOME PHARMA CORP. (CA) | 2005-12-01 | — | — | WO | claimed |
| US-5039673-A | Anticoagulants, bronchodilators, vasodilators | GLAXO GROUP LIMITED (GB) | 1991-08-13 | — | — | US | disclosed |
| US-4880800-A | PROSTAGLANDIN DERIVATIVES FOR ANTICOAGULANTS, VASODILATION, BRONCHODILATION | GLAXO GROUP LIMITED (GB) | 1989-11-14 | — | — | US | disclosed |
| EP-0297855-A1 | Aminocyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1989-01-04 | — | — | EP | disclosed |
| EP-0296802-A1 | Aminocyclopentyl ethers and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1988-12-28 | — | — | EP | disclosed |