⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25992902 | 1.00 | — | — | |
| SCHEMBL13589461 | 0.82 | — | — | |
| SCHEMBL2352644 | 0.80 | — | — | |
| SCHEMBL14370535 | 0.78 | — | — | |
| SCHEMBL15692364 | 0.76 | — | — | |
| SCHEMBL21827458 | 0.76 | — | — | |
| SCHEMBL21827980 | 0.76 | — | — | |
| SCHEMBL22484527 | 0.76 | — | — | |
| SCHEMBL16666823 | 0.76 | — | — | |
| SCHEMBL16666820 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624033-B2 | KRAS inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-05-12 | — | — | US | disclosed |
| EP-4735439-A1 | KRAS INHIBITORS | Bristol-Myers Squibb Company (US) | 2026-05-06 | — | — | EP | disclosed |
| EP-4735440-A1 | KRAS INHIBITORS | Bristol-Myers Squibb Company (US) | 2026-05-06 | — | — | EP | disclosed |
| US-20250304537-A1 | HETEROARENES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME | REPARE THERAPEUTICS INC. (CA) | 2025-10-02 | — | — | US | disclosed |
| US-20250250271-A1 | KRAS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2025-08-07 | — | — | US | disclosed |
| US-12331026-B2 | Sulfonamido derivatives as cyclin-dependent kinase 2 inhibitors | NIKANG THERAPEUTICS, INC. (US) | 2025-06-17 | — | — | US | disclosed |
| EP-4554945-A1 | PYRROLOTRIAZINE AND IMIDAZOTRIAZINE DERIVATIVES AS MODULATORS OF THE NLRP3 INFLAMMASOME PATHWAY | AC Immune SA (CH) | 2025-05-21 | — | — | EP | disclosed |
| US-20250154148-A1 | KRAS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2025-05-15 | — | — | US | disclosed |
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MRJA THERAPEUTICS, INC. | 2025-05-08 | — | — | US | disclosed |
| CN-119907802-A | Pyrrolotriazine and imidazotriazine derivatives as modulators of NLRP3 inflammatory small body pathways | AC免疫有限公司 | 2025-04-29 | — | — | CN | disclosed |
| US-20200108075-A1 | 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF | GENENTECH, INC. (US) | 2020-04-09 | — | — | US | disclosed |
| CN-107109040-B | Polytrimethylene terephthalate composition, polyester fiber and its manufacturing method | 帝人富瑞特株式会社 | 2019-06-28 | — | — | CN | disclosed |
| CN-109694470-A | A kind of preparation method of high heat resistance amorphous polyester | 中国石化仪征化纤有限责任公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-109694468-A | The preparation method of high heat resistance bottle modified poly ester | 中国石化仪征化纤有限责任公司 | 2019-04-30 | — | — | CN | disclosed |
| WO-2019048541-A1 | 1-(4-(ISOXAZOL-5-YL)-1H-PYRAZOL-1-YL)-2-METHYLPROPAN-2-OL DERIVATIVES AND RELATED COMPOUNDS AS IL-17 AND IFN-GAMMA INHIBITORS FOR TREATING AUTOIMMUNE DISEASES AND CHRONIC INFLAMMATION | IMMUNIC AG (DE) | 2019-03-14 | — | — | WO | disclosed |
| US-20090023885-A1 | TREATMENT METHOD FOR IMPARTING HIGH IMPACT RESISTANCE IN CERTAIN CBDO COPOLYMERS | TEXAS STATE UNIVERSITY - SAN MARCOS (US) | 2009-01-22 | — | — | US | disclosed |
| EP-1899401-A1 | FILM(S)AND/OR SHEET(S) COMPRISING POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL AND HAVE A CERTAIN COMBINATION OF INHERENT VISCOSITY AND HIGH GLASS TRANSITION TEMPERATURE | EASTMAN CHEMICAL COMPANY (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007001565-A1 | FILM(S)AND/OR SHEET(S) COMPRISING POLYESTER COMPOSITIONS WHICH COMPRISE CYCLOBUTANEDIOL AND HAVE A CERTAIN COMBINATION OF INHERENT VISCOSITY AND HIGH GLASS TRANSITION TEMPERATURE | EASTMAN CHEMICAL COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |
| WO-1995012640-A1 | THERMOSETTING COATING COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 1995-05-11 | — | — | WO | disclosed |
| WO-1991004285-A1 | NON-CRYSTALLINE ACETAL COPOLYMER ELASTOMERS | HOECHST CELANESE CORP (US) | 1991-04-04 | — | — | WO | disclosed |