⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702146 | 0.81 | — | — | |
| SCHEMBL4618629 | 0.69 | — | — | |
| SCHEMBL42667 | 0.66 | — | — | |
| SCHEMBL319783 | 0.65 | — | — | |
| SCHEMBL9915570 | 0.65 | — | — | |
| SCHEMBL11295633 | 0.65 | — | — | |
| SCHEMBL6144841 | 0.61 | — | — | |
| SCHEMBL9134442 | 0.61 | TRIM24 (0.43) | — | |
| SCHEMBL10330414 | 0.61 | — | — | |
| SCHEMBL21652329 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239895-A1 | Novel 3-thia-10-aza-phenanthrene derivatives | NYCOMED GMBH (DE) | 2009-09-24 | — | — | US | claimed |
| US-20080103168-A1 | Novel 3-Thia-10-Aza-Phenanthrene Derivatives | ATLANA PHARMA AG (DE) | 2008-05-01 | — | — | US | claimed |
| EP-1791847-A2 | NOVEL 3-THIA-10-AZA-PHENANTHRENE DERIVATIVES | Altana Pharma AG (DE) | 2007-06-06 | — | — | EP | claimed |
| WO-2006027345-A2 | NOVEL 3-THIA-10-AZA-PHENANTHRENE DERIVATIVES | ALTANA PHARMA AG (DE) | 2006-03-16 | — | — | WO | claimed |
| CN-114761432-A | Dosing regimen of anti-CD 27 antibodies for treatment of cancer | 默沙东公司 | 2022-07-15 | — | — | CN | disclosed |
| WO-2022059609-A1 | PRESSURE-SENSITIVE-ADHESIVE POLARIZING FILM, AND LAMINATE FOR IMAGE DISPLAY DEVICE | 綜研化学株式会社 | 2022-03-24 | — | — | WO | disclosed |
| EP-3416638-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV Pharmaceuticals, Inc. (US) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017143291-A1 | METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION | PMV PHARMACEUTICALS, INC. (US) | 2017-08-24 | — | — | WO | disclosed |
| US-8324404-B2 | 3-thia-10-aza-phenanthrene derivatives | NYCOMED GMBH (DE) | 2012-12-04 | — | — | US | disclosed |
| US-20090239895-A1 | Novel 3-thia-10-aza-phenanthrene derivatives | NYCOMED GMBH (DE) | 2009-09-24 | — | — | US | disclosed |
| US-7589205-B2 | phosphodiesterase inhibitor; antiinflammatory agent; 3-thia-10-aza-phenanthrenes and iintermediates 3-(3,4-dialkoxy-phenyl)-tetrahydro-thiopyran-4-one and 3-(3,4-dialkoxy-phenyl)-1,1-dioxo-hexahydro-1-thiopyran-4-ylamine, useful for its preparation | NYCOMED GMBH (DE) | 2009-09-15 | — | — | US | disclosed |
| US-20080103168-A1 | Novel 3-Thia-10-Aza-Phenanthrene Derivatives | ATLANA PHARMA AG (DE) | 2008-05-01 | — | — | US | disclosed |
| EP-1791847-A2 | NOVEL 3-THIA-10-AZA-PHENANTHRENE DERIVATIVES | Altana Pharma AG (DE) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006027345-A2 | NOVEL 3-THIA-10-AZA-PHENANTHRENE DERIVATIVES | ALTANA PHARMA AG (DE) | 2006-03-16 | — | — | WO | disclosed |