⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866547 | 0.69 | GAA (0.37) | — | |
| SCHEMBL1919337 | 0.68 | — | — | |
| SCHEMBL3886432 | 0.66 | — | — | |
| SCHEMBL2166445 | 0.65 | — | — | |
| SCHEMBL1225481 | 0.63 | — | — | |
| SCHEMBL3885172 | 0.62 | — | — | |
| SCHEMBL9458897 | 0.62 | — | — | |
| SCHEMBL7937128 | 0.62 | — | — | |
| SCHEMBL10692876 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL17593296 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989209-B1 | Aza-thia-benzazulene derivatives and pharmaceutical use thereof | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-03-25 | — | — | EP | disclosed |
| EP-1989209-B1 | Aza-thia-benzazulene derivatives and pharmaceutical use thereof | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-03-25 | — | — | EP | disclosed |
| US-8258128-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-09-04 | — | — | US | disclosed |
| US-8258128-B2 | Organic compounds | NOVARTIS AG (CH) | 2012-09-04 | — | — | US | disclosed |
| CN-101389633-B | Organic compounds | NOVARTIS AG | 2011-08-24 | — | — | CN | disclosed |
| US-20090131408-A1 | Organic Compounds | NOVARTIS TIERGESUNDHEIT AG (CH) | 2009-05-21 | — | — | US | disclosed |
| US-20090131408-A1 | Organic Compounds | NOVARTIS TIERGESUNDHEIT AG (CH) | 2009-05-21 | — | — | US | disclosed |
| CN-101389633-A | Organic compounds | NOVARTIS AG (CH) | 2009-03-18 | — | — | CN | disclosed |
| EP-1989209-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-11-12 | — | — | EP | disclosed |
| EP-1989209-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007096150-A3 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007096150-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-08-30 | — | — | WO | disclosed |
| WO-2007096150-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2007-08-30 | — | — | WO | disclosed |