Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510207 | 0.89 | HDAC1 (0.55) | MEN1MAPTKMT2AAURKAKDR | |
| SCHEMBL15697598 | 0.82 | MEN1 (0.55) | MEN1MAPTKMT2AHDAC1TBXAS1 | |
| SCHEMBL5809799 | 0.81 | HDAC1 (0.67) | MEN1MAPTKMT2AHDAC1TBXAS1 | |
| SCHEMBL15697524 | 0.76 | PPARA (0.53) | MEN1MAPTKMT2AHDAC1TBXAS1 | |
| SCHEMBL18893616 | 0.76 | HDAC1 (0.54) | MEN1MAPTKMT2AHDAC1BCL2L1 | |
| SCHEMBL15697526 | 0.76 | MAPT (0.82) | MEN1MAPTKMT2AHDAC1POLB | |
| SCHEMBL17135415 | 0.74 | HDAC1 (0.55) | MEN1MAPTKMT2AHDAC1TBXAS1 | |
| SCHEMBL19880960 | 0.74 | BCL2L1 (0.51) | MEN1MAPTKMT2AHDAC1TBXAS1 | |
| SCHEMBL15697492 | 0.73 | MEN1 (0.64) | MEN1MAPTKMT2AHDAC1 | |
| SCHEMBL27724012 | 0.73 | MAPT (0.67) | MEN1MAPTKMT2AHDAC1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227571-A1 | Androgen Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED | 2009-09-10 | — | — | US | claimed |
| US-20090227571-A1 | Androgen Receptor Modulator Compounds and Methods | LIGAND PHARMACEUTICALS INCORPORATED | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227571-A1 | Androgen Receptor Modulator Compounds and Methods | AR, NR5A1, ESRRA | MEN1 3667/4885MAPT 4208/4885KMT2A 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.