Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4178008 | 1.00 | TDP1 (0.57) | TDP1L3MBTL1MEN1CYP1A2CHRM2 | |
| SCHEMBL29991217 | 1.00 | TDP1 (0.57) | TDP1L3MBTL1MEN1CYP1A2CHRM2 | |
| SCHEMBL29384939 | 1.00 | TDP1 (0.57) | TDP1L3MBTL1MEN1CYP1A2CHRM2 | |
| SCHEMBL4167098 | 1.00 | TDP1 (0.57) | TDP1L3MBTL1MEN1CYP1A2CHRM2 | |
| SCHEMBL11502328 | 1.00 | TDP1 (0.57) | TDP1L3MBTL1MEN1CYP1A2CHRM2 | |
| SCHEMBL25123877 | 1.00 | TDP1 (0.57) | TDP1L3MBTL1MEN1CYP1A2CHRM2 | |
| SCHEMBL19585886 | 1.00 | TDP1 (0.57) | TDP1L3MBTL1MEN1CYP1A2CHRM2 | |
| SCHEMBL4190379 | 0.98 | TDP1 (0.54) | TDP1L3MBTL1HDAC8HDAC3HDAC4 | |
| SCHEMBL2286757 | 0.93 | TDP1 (0.51) | TDP1L3MBTL1MEN1CYP1A2CHRM2 | |
| SCHEMBL18374260 | 0.90 | TDP1 (0.47) | TDP1L3MBTL1MEN1CYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009086835-A1 | NOVEL CYANOGUANIDINES | TOPOTARGET A/S (DK) | 2009-07-16 | — | — | WO | disclosed |