Bromide

Bromide

SCHEMBL4183722

S=C(S)c1ccccc1.[Br-].[Br-].[Mg+2]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA3 P07451 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA13 Q8N1Q1 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
ALDH1A1 P00352 4/20 0.42
MAPT P10636 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.41
MEN1 O00255 2/20 0.41
HPGD P15428 2/20 0.41
KMT2A Q03164 2/20 0.41
HSP90AA1 P07900 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28151406 0.94 CA12 (0.52) CA12CA1CA2CA3CA4
SCHEMBL28330913 0.94 CA12 (0.52) CA12CA1CA2CA3CA4
SCHEMBL35105 0.94
Methane SCHEMBL27922230 0.92 CA12 (0.50) CA12CA1CA2CA3CA4
Ammonia Solution, Strong SCHEMBL2372816 0.92 CA12 (0.50) CA12CA1CA2CA3CA4
SCHEMBL27884811 0.92 CA12 (0.50) CA12CA1CA2CA3CA4
SCHEMBL4661390 0.92 CA12 (0.50) CA12CA1CA2CA3CA4
Hydrogen Sulfide SCHEMBL1254845 0.92 CA12 (0.50) CA12CA1CA2CA3CA4
SCHEMBL27924120 0.92 CA12 (0.50) CA12CA1CA2CA3CA4
SCHEMBL28215676 0.84 CA12 (0.44) CA12CA1CA2CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103132321-B Preparation method for carbon nanofiber graft polymer for carbon black dispersion CAS GUANGZHOU CHEMISTRY CO LTD 2014-08-20 CN claimed
CN-103132321-A Preparation method for carbon nanofiber graft polymer for carbon black dispersion CAS GUANGZHOU CHEMISTRY CO LTD 2013-06-05 CN claimed
CN-102994073-A Benzoxazole-based fluorescent-identified RAFT reagent, synthesis method and application UNIV TIANJIN 2013-03-27 CN claimed
CN-103132321-B Preparation method for carbon nanofiber graft polymer for carbon black dispersion CAS GUANGZHOU CHEMISTRY CO LTD 2014-08-20 CN disclosed
CN-103132321-A Preparation method for carbon nanofiber graft polymer for carbon black dispersion CAS GUANGZHOU CHEMISTRY CO LTD 2013-06-05 CN disclosed
CN-102994073-A Benzoxazole-based fluorescent-identified RAFT reagent, synthesis method and application UNIV TIANJIN 2013-03-27 CN disclosed
JP-2009269835-A METHOD FOR PRODUCING 2-CYANOPROP-2-YLDITHIOBENZOATE AND POLYMERIZATION METHOD USING THE SAME MITSUBISHI RAYON CO LTD 2009-11-19 JP disclosed