SCHEMBL4183756

SCHEMBL4183756

Cc1cc(SC(CCCCc2ccccc2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 1.00
PPARA Q07869 5/20 0.83

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4181742 0.99 PPARD (1.00) PPARDPPARA
SCHEMBL4174438 0.99 PPARD (1.00) PPARDPPARA
SCHEMBL4187308 0.99 PPARD (1.00) PPARDPPARA
SCHEMBL4174621 0.98 PPARD (1.00) PPARDPPARA
SCHEMBL4174634 0.95 PPARD (1.00) PPARDPPARA
SCHEMBL4181834 0.91 PPARD (0.86) PPARDPPARA
SCHEMBL5217114 0.90 PPARD (1.00) PPARDPPARA
SCHEMBL11926058 0.90 PPARD (1.00) PPARDPPARA
SCHEMBL11926063 0.90 PPARD (1.00) PPARDPPARA
SCHEMBL11926061 0.90 PPARD (1.00) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090054493-A1 THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS Kang, Heonjoong Kang (KR) 2009-02-26 US disclosed
EP-1856072-A1 THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS Kang, Heonjoong (KR) 2007-11-21 EP disclosed
WO-2006091047-A1 THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS KANG HEONJOONG (KR) 2006-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054493-A1 THIAZOLE DERIVATIVES AS PPAR DELTA LIGANDS AND THEIR MANUFACTURING PROCESS PPARD, PPARG, PPARA PPARD 1/4885PPARA 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.