Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.66 |
| ▸ | HSD17B1 | P14061 | 6/20 | 0.66 |
| ▸ | STS | P08842 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.66 |
| ▸ | ESR1 | P03372 | 1/20 | 0.66 |
| ▸ | SHBG | P04278 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | AR | P10275 | 1/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13804527 | 1.00 | HSD17B10 (0.69) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL14569770 | 0.87 | HSD17B10 (0.70) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL11458465 | 0.87 | HSD17B10 (0.70) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL11687810 | 0.87 | MEN1 (0.74) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL11692049 | 0.87 | MEN1 (0.74) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL13930476 | 0.87 | HSD17B10 (0.70) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL15971654 | 0.87 | MEN1 (0.74) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL29198757 | 0.87 | MEN1 (0.74) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| Methoxymethane SCHEMBL10335838 | 0.84 | MEN1 (0.70) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 | |
| SCHEMBL5681977 | 0.84 | AKR1C3 (0.79) | HSD17B10AKR1C3TSHRMAPK1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156843-A1 | PROCESS FOR AROMATIZING 19-NORANDROST-4-EN-3-ONES TO ESTRA-1,3,5(10)-TRIENES | BAYER SCHERING PHARMA AG (DE) | 2009-06-18 | — | — | US | disclosed |
| EP-2070942-A1 | Method for aromatising 19-nor-androst-4-en-3-ones to estra-1,3,5(10)-trienes | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-06-17 | — | — | EP | disclosed |
| EP-1226155-B1 | 18-NOR-STEROIDS AS SELECTIVELY ACTIVE ESTROGENS | BAYER SCHERING PHARMA AG (DE) | 2007-05-02 | — | — | EP | disclosed |
| US-20050282791-A1 | 18-nor steroids as selectively active estrogens | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-12-22 | — | — | US | disclosed |
| US-6958327-B1 | 18 Norsteroids as selectively active estrogens | SCHERING, AG (DE) | 2005-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156843-A1 | PROCESS FOR AROMATIZING 19-NORANDROST-4-EN-3-ONES TO ESTRA-1,3,5(10)-TRIENES | CYP19A1, HSD17B11, NR5A1 | HSD17B10 37/4885AKR1C3 70/4885TSHR 1668/4885 |
| US-20050282791-A1 | 18-nor steroids as selectively active estrogens | GPER1, ESR2, ESRRA | HSD17B10 370/4885AKR1C3 409/4885TSHR 389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.