Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4187801 | 1.00 | CNR1 (0.53) | CNR1LPAR3LPAR1GRIA1TLR2 | |
| SCHEMBL4174364 | 1.00 | CNR1 (0.53) | CNR1LPAR3LPAR1GRIA1TLR2 | |
| SCHEMBL4187790 | 1.00 | CNR1 (0.53) | CNR1LPAR3LPAR1GRIA1TLR2 | |
| SCHEMBL4190947 | 1.00 | CNR1 (0.53) | CNR1LPAR3LPAR1GRIA1TLR2 | |
| SCHEMBL4191446 | 1.00 | CNR1 (0.53) | CNR1LPAR3LPAR1GRIA1TLR2 | |
| SCHEMBL4183430 | 1.00 | CNR1 (0.53) | CNR1LPAR3LPAR1GRIA1TLR2 | |
| SCHEMBL4183470 | 0.99 | CNR1 (0.51) | CNR1LPAR3LPAR1GRIA1TLR2 | |
| SCHEMBL4185123 | 0.84 | LPAR3 (0.50) | LPAR3LPAR1ITGB3ITGA2B | |
| SCHEMBL4187715 | 0.84 | LPAR3 (0.50) | LPAR3LPAR1ITGB3ITGA2B | |
| SCHEMBL4190836 | 0.84 | LPAR3 (0.50) | LPAR3LPAR1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8283339-B2 | Vinyl phosphonate lysophosphatidic acid receptor antagonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-8283339-B2 | Vinyl phosphonate lysophosphatidic acid receptor antagonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-8283339-B2 | Vinyl phosphonate lysophosphatidic acid receptor antagonists | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2012-10-09 | — | — | US | disclosed |
| US-20090197835-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-08-06 | — | — | US | disclosed |
| US-20090197835-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-08-06 | — | — | US | disclosed |
| US-20090197835-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2009-08-06 | — | — | US | disclosed |
| WO-2008014286-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2008-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197835-A1 | VINYL PHOSPHONATE LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR4, LPAR5 | CNR1 153/4885LPAR3 6/4885LPAR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.