Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13666895 | 0.94 | KDM4E (0.62) | KDM4EHTTHSD17B10MAPTTP53 | |
| SCHEMBL32670901 | 0.90 | KDM4E (0.54) | KDM4EHTTHSD17B10MAPTTP53 | |
| SCHEMBL9713872 | 0.86 | KDM4E (0.59) | KDM4EHTTHSD17B10MAPTTP53 | |
| SCHEMBL29368738 | 0.83 | KDM4E (0.63) | KDM4EHTTHSD17B10MAPTTP53 | |
| SCHEMBL6907648 | 0.83 | KDM4E (0.63) | KDM4EHTTHSD17B10MAPTTP53 | |
| SCHEMBL9629451 | 0.81 | KDM4E (0.54) | KDM4EHTTHSD17B10MAPTTP53 | |
| SCHEMBL9627616 | 0.81 | KDM4E (0.54) | KDM4EHTTHSD17B10MAPTTP53 | |
| SCHEMBL11780453 | 0.81 | KDM4E (0.61) | KDM4EHTTHSD17B10MAPTTP53 | |
| SCHEMBL24596055 | 0.79 | KDM4E (0.57) | KDM4EHTTHSD17B10MAPTTP53 | |
| SCHEMBL11784762 | 0.79 | KDM4E (0.51) | KDM4EHTTHSD17B10MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029510-A1 | PATCHOULI ODORANT | Firmenich SA (CH) | 2009-03-04 | — | — | EP | claimed |
| WO-2007135582-A1 | PATCHOULI ODORANT | FIRMENICH SA (CH) | 2007-11-29 | — | — | WO | claimed |