⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11036105 | 0.75 | — | — | |
| SCHEMBL168040 | 0.70 | — | — | |
| SCHEMBL11362394 | 0.67 | — | — | |
| SCHEMBL3888374 | 0.67 | — | — | |
| SCHEMBL17681498 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL8326110 | 0.67 | — | — | |
| SCHEMBL42968 | 0.65 | GRIN2D (0.33) | — | |
| SCHEMBL11368086 | 0.64 | — | — | |
| SCHEMBL1041997 | 0.64 | — | — | |
| SCHEMBL1951442 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7541488-B2 | Process for the preparation of mono- and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates | MERCK PATENT GMBH (DE) | 2009-06-02 | — | — | US | disclosed |
| EP-1685143-B1 | METHOD FOR THE PRODUCTION OF MONO(FLUOROALKYL)PHOSPHORANES, BIS(FLUOROALKYL)PHOSPHORANES, AND THE CORRESPONDING ACIDS AND PHOSPHATES | MERCK PATENT GMBH (DE) | 2007-11-28 | — | — | EP | disclosed |
| US-20070088176-A1 | Process for the preparation of mono-and bis(fluoroalkyl)phosphoranes and the corresponding acids and phosphates | MERECK PATENT GMBH (DE) | 2007-04-19 | — | — | US | disclosed |
| EP-1685143-A1 | METHOD FOR THE PRODUCTION OF MONO(FLUOROALKYL)PHOSPHORANES, BIS(FLUOROALKYL)PHOSPHORANES, AND THE CORRESPONDING ACIDS AND PHOSPHATES | Merck Patent GmbH (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005049628-A1 | METHOD FOR THE PRODUCTION OF MONO(FLUOROALKYL)PHOSPHORANES, BIS(FLUOROALKYL)PHOSPHORANES, AND THE CORRESPONDING ACIDS AND PHOSPHATES | MERCK PATENT GMBH (DE) | 2005-06-02 | — | — | WO | disclosed |