Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 2/20 | 0.37 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | NR1D2 | Q14995 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7147901 | 0.96 | MAPK9 (0.41) | MAPK9MAPK10MEN1KMT2ARORC | |
| SCHEMBL3480484 | 0.89 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ATGM2 | |
| SCHEMBL3480019 | 0.88 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL3480021 | 0.88 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2AALDH1A1 | |
| SCHEMBL4198093 | 0.88 | MAPK9 (0.47) | MAPK9MAPK10MEN1KMT2ARORC | |
| SCHEMBL3479910 | 0.86 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ARORC | |
| SCHEMBL3479914 | 0.86 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ARORC | |
| SCHEMBL3479846 | 0.85 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ATGM2 | |
| SCHEMBL3480010 | 0.85 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ATGM2 | |
| SCHEMBL3480409 | 0.85 | MAPK9 (0.53) | MAPK9MAPK10MEN1KMT2ATGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |