Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479940 | 0.94 | KMT2A (0.51) | MEN1KMT2ADRD4GAATSHR | |
| SCHEMBL3480044 | 0.93 | KMT2A (0.48) | MEN1KMT2AGAATSHRL3MBTL1 | |
| SCHEMBL3479873 | 0.91 | KMT2A (0.51) | MEN1KMT2ADRD4GAATSHR | |
| SCHEMBL3480012 | 0.90 | MEN1 (0.48) | MEN1KMT2ADRD4GAAL3MBTL1 | |
| SCHEMBL3480243 | 0.89 | KMT2A (0.49) | MEN1KMT2AGAATSHRCYP2C9 | |
| SCHEMBL3480003 | 0.88 | KMT2A (0.53) | MEN1KMT2AGAATSHRL3MBTL1 | |
| SCHEMBL3480121 | 0.87 | MEN1 (0.48) | MEN1KMT2ADRD4TSHRL3MBTL1 | |
| SCHEMBL3479921 | 0.82 | KMT2A (0.55) | MEN1KMT2AGAAL3MBTL1NPC1 | |
| SCHEMBL3479992 | 0.81 | KMT2A (0.51) | MEN1KMT2AGAATSHRL3MBTL1 | |
| SCHEMBL3479854 | 0.81 | KMT2A (0.53) | MEN1KMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |