SCHEMBL4189949

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4182953	0.95	PPARD (0.54)	PPARAPPARDPPARGALDH1A1L3MBTL1
	SCHEMBL4620806	0.84	PPARD (0.71)	PPARAPPARDPPARG
	SCHEMBL4185346	0.84	PPARG (0.53)	PPARAPPARDPPARGALDH1A1HDAC3
	SCHEMBL4184384	0.84	PPARD (0.63)	PPARAPPARDPPARGALDH1A1L3MBTL1
	SCHEMBL4193737	0.84	PPARD (0.63)	PPARAPPARDPPARGALDH1A1L3MBTL1
	SCHEMBL4191088	0.82	HDAC3 (0.52)	PPARAPPARDPPARGALDH1A1L3MBTL1
	SCHEMBL4185351	0.81	PPARD (0.64)	PPARAPPARDPPARG
	SCHEMBL4194429	0.80	PPARD (0.54)	PPARAPPARDPPARGALDH1A1L3MBTL1
	SCHEMBL4194384	0.79	HDAC3 (0.51)	PPARAPPARDPPARGALDH1A1L3MBTL1
	SCHEMBL4183003	0.78	PPARD (0.83)	PPARAPPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.