Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AKT2 | P31751 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336074 | 0.58 | — | — | |
| SCHEMBL17561029 | 0.56 | AKT2 (0.58) | CHEK1AKT2 | |
| SCHEMBL14826495 | 0.56 | ADORA2A (0.42) | CYP1A2PDPK1 | |
| SCHEMBL12657752 | 0.55 | — | — | |
| SCHEMBL25332682 | 0.55 | PDPK1 (0.34) | CYP1A2PDPK1 | |
| SCHEMBL170835 | 0.53 | GDA (0.35) | — | |
| SCHEMBL19154248 | 0.53 | PDPK1 (0.40) | CYP1A2PDPK1 | |
| SCHEMBL24000490 | 0.53 | GRIN2D (0.43) | CYP1A2PDPK1 | |
| SCHEMBL24131106 | 0.53 | — | — | |
| SCHEMBL16209719 | 0.53 | AKT2 (0.79) | CHEK1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024360-A2 | SUBSTITUTED PYRAZOLOPYRIMIDINES | Cephalon, Inc. (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2008063232-A2 | SUBSTITUTED PYRAZOLOPYRIMIDINES | CEPHALON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |