Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425856 | 0.90 | KMT2A (0.54) | CCR3KMT2AMEN1NPC1APOBEC3A | |
| SCHEMBL2423644 | 0.86 | KMT2A (0.53) | CCR3KMT2AMEN1NPC1APOBEC3A | |
| SCHEMBL2423449 | 0.86 | KMT2A (0.58) | CCR3KMT2AMEN1NPC1APOBEC3A | |
| SCHEMBL2423174 | 0.85 | KMT2A (0.59) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2421857 | 0.83 | KMT2A (0.52) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2429271 | 0.83 | KMT2A (0.53) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2422541 | 0.83 | KMT2A (0.56) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2423231 | 0.82 | KMT2A (0.55) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL6431623 | 0.82 | KMT2A (0.55) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G | |
| SCHEMBL2424314 | 0.81 | KMT2A (0.53) | KMT2AMEN1NPC1APOBEC3AAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |