Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 16/20 | 0.66 |
| ▸ | ROS1 | P08922 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022175 | 0.80 | ROS1 (0.73) | TRPV1ROS1RPS6KB1NAMPTALDH1A1 | |
| SCHEMBL4019245 | 0.79 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL4027196 | 0.77 | TRPV1 (0.67) | TRPV1ROS1RPS6KB1NAMPTALDH1A1 | |
| SCHEMBL4022888 | 0.77 | TRPV1 (0.67) | TRPV1ROS1RPS6KB1NAMPTALDH1A1 | |
| SCHEMBL4021359 | 0.77 | TRPV1 (0.66) | TRPV1ROS1RPS6KB1NAMPTALDH1A1 | |
| SCHEMBL4021068 | 0.75 | TRPV1 (0.64) | TRPV1ROS1RPS6KB1NAMPTALDH1A1 | |
| SCHEMBL4022681 | 0.74 | TRPV1 (0.63) | TRPV1ROS1RPS6KB1NAMPTALDH1A1 | |
| SCHEMBL4025322 | 0.74 | TRPV1 (0.62) | TRPV1ROS1RPS6KB1NAMPTALDH1A1 | |
| SCHEMBL4023713 | 0.73 | TRPV1 (0.61) | TRPV1ROS1RPS6KB1NAMPTALDH1A1 | |
| SCHEMBL4021182 | 0.73 | TRPV1 (0.61) | TRPV1ROS1RPS6KB1NAMPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478363-B1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LAB (US) | 2009-01-14 | — | — | EP | claimed |