Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2719075 | 0.89 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL31041060 | 0.88 | EPHX2 (0.78) | EPHX2EPHX1 | |
| SCHEMBL15170943 | 0.87 | EPHX2 (0.84) | EPHX2EPHX1 | |
| SCHEMBL2716676 | 0.86 | EPHX2 (0.82) | EPHX2EPHX1 | |
| SCHEMBL2719652 | 0.86 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL4012354 | 0.86 | EPHX2 (0.76) | EPHX2EPHX1 | |
| SCHEMBL5143669 | 0.85 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL2716978 | 0.84 | EPHX2 (1.00) | EPHX2EPHX1 | |
| SCHEMBL14433541 | 0.84 | EPHX2 (0.81) | EPHX2EPHX1 | |
| SCHEMBL4011010 | 0.84 | EPHX2 (0.83) | EPHX2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029539-A1 | PIPERIDINYL, INDOLYL, PIRINIDYL, MORPHOLINYL AND BENZIMIDAZOLYL UREA DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE FOR THE TREATMENT OF HYPERTENSION, INFLAMMATIONS AND OTHER DISEASES | The Regents of the University of California (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007106525-A1 | PIPERIDINYL, INDOLYL, PIRINIDYL, MORPHOLINYL AND BENZIMIDAZOLYL UREA DERIVATIVES AS INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE FOR THE TREATMENT OF HYPERTENSION, INFLAMMATIONS AND OTHER DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-09-20 | — | — | WO | disclosed |