Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3479961 | 0.92 | KMT2A (0.55) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3480163 | 0.92 | KMT2A (0.54) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3479863 | 0.92 | KMT2A (0.58) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3480254 | 0.91 | KMT2A (0.55) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3479836 | 0.90 | KMT2A (0.52) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3479968 | 0.90 | KMT2A (0.52) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3479987 | 0.90 | KMT2A (0.52) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3479831 | 0.89 | KMT2A (0.55) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3479988 | 0.89 | KMT2A (0.51) | KMT2AMEN1PKMNPC1APOBEC3A | |
| SCHEMBL3479955 | 0.89 | KMT2A (0.53) | KMT2AMEN1PKMNPC1APOBEC3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2026802-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | Laboratoires Serono SA (CH) | 2009-02-25 | — | — | EP | disclosed |
| WO-2007141224-A2 | JNK INHIBITORS FOR TREATMENT OF SKIN DISEASES | LABORATOIRES SERONO SA (CH) | 2007-12-13 | — | — | WO | disclosed |