Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203688 | 0.63 | — | — | |
| SCHEMBL14592161 | 0.56 | — | — | |
| SCHEMBL3724213 | 0.55 | — | — | |
| SCHEMBL47224 | 0.53 | — | — | |
| SCHEMBL23921503 | 0.52 | — | — | |
| SCHEMBL24862847 | 0.52 | CNR2 (0.31) | — | |
| Potassium SCHEMBL31174422 | 0.51 | — | — | |
| SCHEMBL31686392 | 0.51 | — | — | |
| SCHEMBL25592429 | 0.51 | — | — | |
| SCHEMBL30471938 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1717226-B1 | 2,7-SUBSTITUTED 5-AMINO-4-HYDROXY-8-(1H-INDOL-5-YL)-OCTAN AMIDE DERIVATIVES AS RENIN INHIBITORS FOR THE TREATMENT OF HYPERTENSION | SPEEDEL EXPERIMENTA AG (CH) | 2009-01-21 | — | — | EP | claimed |