⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17771931 | 0.94 | — | — | |
| SCHEMBL42308 | 0.94 | — | — | |
| Lithium SCHEMBL31244596 | 0.89 | — | — | |
| SCHEMBL43526 | 0.89 | — | — | |
| Water SCHEMBL27695991 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL11747356 | 0.89 | — | — | |
| SCHEMBL11835564 | 0.89 | — | — | |
| SCHEMBL19712285 | 0.89 | — | — | |
| SCHEMBL21065697 | 0.89 | — | — | |
| SCHEMBL28190533 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373951-B | A kind of preparation method of lapatinib intermediate | SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) | 2016-03-09 | — | — | CN | disclosed |
| CN-103373951-A | Preparation method of Tykerb intermediate | SHANGHAI INST PHARM INDUSTRY | 2013-10-30 | — | — | CN | disclosed |
| EP-1268415-B1 | 26,27-HOMOLOGATED-20-EPI-2-ALKYL-19-NOR-VITAMIN D COMPOUNDS | WISCONSIN ALUMNI RES FOUND (US) | 2013-05-29 | — | — | EP | disclosed |
| CN-100496501-C | Pharmaceutical composition and methods comprising combinations of 2-alkylidene-19-nor-vitamin D derivatives and an estrogen agonist/antagonist | WISCONSIN ALUMNI RES FOUND (US) | 2009-06-10 | — | — | CN | disclosed |
| US-20090143342-A1 | 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION OF MADISON | 2009-06-04 | — | — | US | disclosed |
| CN-100413507-C | 2-alkylidene-19-nor-vitamin d derivatives for the treatment of osteopenia or male osteoporosis | PFIZER (US) | 2008-08-27 | — | — | CN | disclosed |
| EP-1268416-B1 | 2-ALKYLIDENE-19-NOR-VITAMIN D COMPOUNDS AND THEIR THERAPEUTIC USES | WISCONSIN ALUMNI RES FOUND (US) | 2007-09-26 | — | — | EP | disclosed |
| CN-1852716-A | Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and parathyroid hormone | PFIZER (US) | 2006-10-25 | — | — | CN | disclosed |
| CN-1852718-A | 2-alkylidene-19-nor-vitamin D derivatives for the treatment of frailty, muscle damage or sarcopenia | PFIZER (US) | 2006-10-25 | — | — | CN | disclosed |
| CN-1852720-A | Pharmaceutical composition and methods comprising combinations of 2-alkylidene-19-nor-vitamin D derivatives and an estrogen agonist/antagonist | PFIZER (US) | 2006-10-25 | — | — | CN | disclosed |
| EP-0187984-B1 | POLYMERIC MORDANT CONTAINING NITROGEN-COORDINATING LIGAND FOR METALLIZABLE DYES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0187340-B1 | PHOTOGRAPHIC PRODUCTS EMPLOYING NOVEL NONDIFFUSIBLE METAL COMPLEXES OF AZO DYES | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1988-09-21 | — | — | EP | disclosed |
| EP-0187984-A1 | Polymeric mordant containing nitrogen-coordinating ligand for metallizable dyes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-07-23 | — | — | EP | disclosed |
| EP-0187340-A1 | Photographic products employing novel nondiffusible metal complexes of AZO dyes | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-07-16 | — | — | EP | disclosed |
| US-4599389-A | COLOR PHOTOGRAPHY DIFFUSION TRANSFER | EASTMAN KODAK COMPANY (US) | 1986-07-08 | — | — | US | disclosed |
| US-4598030-A | Photographic products employing novel nondiffusible metal complexes of azo dyes | EASTMAN KODAK COMPANY (US) | 1986-07-01 | — | — | US | disclosed |
| US-4581314-A | FOR COLOR DIFFUSION TRANSFER PHOTOGRAPHY; RAPID DYE METALLIZATION | EASTMAN KODAK COMPANY (US) | 1986-04-08 | — | — | US | disclosed |
| US-4562139-A | STABILITY; DIFFUSIBILITY; COLOR FILMS; SELF-DEVELOPMENT | EASTMAN KODAK COMPANY (US) | 1985-12-31 | — | — | US | disclosed |
| US-4216320-A | Quinoxaline bleach catalysts | CIBA-GEIGY AG (CH) | 1980-08-05 | — | — | US | disclosed |
| US-4145217-A | DYE BLEACH CATALYST | CIBA-GEIGY AG (CH) | 1979-03-20 | — | — | US | disclosed |