Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | IDH2 | P48735 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4202692 | 0.83 | ADORA2A (0.39) | SMN1; SMN2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4199549 | 0.74 | ADORA2A (0.39) | SMN1; SMN2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4192282 | 0.72 | ADORA2A (0.39) | SMN1; SMN2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4185762 | 0.72 | — | — | |
| SCHEMBL4194799 | 0.72 | CA1 (0.31) | SMN1; SMN2HTT | |
| SCHEMBL4189572 | 0.72 | ADORA2A (0.41) | SMN1; SMN2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4199543 | 0.72 | ADORA2A (0.39) | SMN1; SMN2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL4953687 | 0.70 | ADORA2A (0.38) | — | |
| SCHEMBL4199532 | 0.70 | ADORA2A (0.38) | — | |
| SCHEMBL4195166 | 0.70 | GLP1R (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090042917-A1 | Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-2006288-A1 | AMINOPYRIDINE DERIVATIVE AND PLANT DISEASE CONTROL AGENT FOR AGRICULTURAL OR HORTICULTURAL USE | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042917-A1 | Aminopyrimidine Derivative and Plant Disease Control Agent for Agricultural or Horticultural Use | DPYD, PM20D2, PDCD11 | SMN1; SMN2 3171/4885IDH1 174/4885IDH2 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.