Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199572 | 1.00 | KCNA5 (1.00) | KCNA5KCNH2 | |
| SCHEMBL3757798 | 1.00 | KCNA5 (1.00) | KCNA5KCNH2 | |
| SCHEMBL4558534 | 0.89 | KCNA5 (0.80) | KCNA5KCNH2 | |
| SCHEMBL3760329 | 0.89 | KCNA5 (1.00) | KCNA5KCNH2 | |
| SCHEMBL3749157 | 0.87 | KCNA5 (1.00) | KCNA5KCNH2 | |
| SCHEMBL3753981 | 0.86 | KCNA5 (0.86) | KCNA5KCNH2 | |
| SCHEMBL3748022 | 0.86 | KCNA5 (0.75) | KCNA5KCNH2 | |
| SCHEMBL3753463 | 0.86 | KCNA5 (1.00) | KCNA5KCNH2 | |
| SCHEMBL3757601 | 0.84 | KCNA5 (1.00) | KCNA5KCNH2 | |
| SCHEMBL3758252 | 0.84 | KCNA5 (1.00) | KCNA5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049484-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | AstraZeneca AB (SE) | 2009-04-22 | — | — | EP | claimed |
| WO-2008008022-A1 | ISOINDOLINE DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2008-01-17 | — | — | WO | claimed |