Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 18/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029633 | 0.86 | TRPV1 (0.64) | TRPV1KDM4EGSK3B | |
| SCHEMBL4027040 | 0.84 | TRPV1 (0.71) | TRPV1KDM4EGSK3BMEN1ALDH1A1 | |
| SCHEMBL4019879 | 0.84 | TRPV1 (0.68) | TRPV1KDM4EGSK3BMEN1ALDH1A1 | |
| SCHEMBL4022743 | 0.83 | TRPV1 (0.70) | TRPV1KDM4EGSK3BMEN1ALDH1A1 | |
| SCHEMBL4022493 | 0.83 | TRPV1 (0.70) | TRPV1KDM4EGSK3BMEN1ALDH1A1 | |
| SCHEMBL4025617 | 0.83 | TRPV1 (0.72) | TRPV1 | |
| SCHEMBL4022819 | 0.82 | TRPV1 (0.70) | TRPV1KDM4EGSK3BMEN1ALDH1A1 | |
| SCHEMBL4022844 | 0.81 | TRPV1 (0.67) | TRPV1KDM4EGSK3BMEN1ALDH1A1 | |
| SCHEMBL4023648 | 0.81 | TRPV1 (0.67) | TRPV1KDM4EGSK3BCYP2D6 | |
| SCHEMBL4019943 | 0.80 | TRPV1 (0.71) | TRPV1KDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478363-B1 | FUSED AZABICYCLIC COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR | ABBOTT LAB (US) | 2009-01-14 | — | — | EP | disclosed |