SCHEMBL4200983

SCHEMBL4200983

c1cc2ccc1CCOCC2

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
CRHBP P24387 2/20 0.35
CRHR2 Q13324 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
HTT P42858 1/20 0.35
APEX1 P27695 1/20 0.34
TTR P02766 1/20 0.33
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL155016 0.71
SCHEMBL2164254 0.71
SCHEMBL30831383 0.71
SCHEMBL16259453 0.69 TTR (0.40) LMNACRHBPCRHR2SMN1; SMN2HTT
SCHEMBL16259447 0.69 TTR (0.40) LMNACRHBPCRHR2SMN1; SMN2HTT
Bromide SCHEMBL4614037 0.68
Hydrochloric Acid SCHEMBL21591829 0.68
SCHEMBL5684789 0.68
SCHEMBL14290532 0.67
SCHEMBL2062312 0.67 TSHR (0.53) LMNACRHBPCRHR2SMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150044450-A1 PRECOATED METAL SHEET FOR AUTOMOBILE USE EXCELLENT IN RESISTANCE WELDABILITY, CORROSION RESISTANCE, AND FORMABILITY NIPPON STEEL CORPORATION (JP) 2015-02-12 US disclosed
EP-2823959-A1 COATED METAL PLATE FOR VEHICLES WHICH EXHIBITS EXCELLENT RESISTANCE WELDABILITY, CORROSION RESISTANCE, AND MOLDABILITY Nippon Steel & Sumitomo Metal Corporation (JP) 2015-01-14 EP disclosed
US-7601775-B2 Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica NIPPON SHOKUBAI CO., LTD. (JP) 2009-10-13 US disclosed
US-20060167164-A1 Fire retardant resin composition, method of its production, shaped articles comprising the same, and silica NIPPON SHOKUBAI CO., LTD. (JP) 2006-07-27 US disclosed
EP-1507829-A1 FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA Nippon Shokubai Co., Ltd. (JP) 2005-02-23 EP disclosed
WO-2003099934-A1 FIRE RETARDANT RESIN COMPOSITION, METHOD OF ITS PRODUCTION, SHAPED ARTICLES COMPRISING THE SAME, AND SILICA NIPPON SHOKUBAI CO., LTD. (JP) 2003-12-04 WO disclosed