Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 19/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.55 |
| ▸ | KDM1A | O60341 | 14/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 13/20 | 0.53 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.52 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4198089 | 0.95 | EHMT2 (0.54) | EHMT2HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL9911788 | 0.91 | EHMT2 (0.51) | EHMT2HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL4198913 | 0.91 | EHMT2 (0.51) | EHMT2HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL1428112 | 0.89 | EHMT2 (0.55) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911778 | 0.89 | EHMT2 (0.59) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL4205091 | 0.89 | EHMT2 (0.61) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL9911777 | 0.89 | EHMT2 (0.67) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1427871 | 0.89 | EHMT2 (0.56) | EHMT2KDM1ARCOR1EZH2PRMT1 | |
| SCHEMBL1427783 | 0.88 | EHMT2 (0.60) | EHMT2KDM1ARCOR1EHMT1EZH2 | |
| SCHEMBL4204774 | 0.88 | EHMT2 (0.58) | EHMT2HDAC1HDAC6HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193203-B2 | Bicyclic compounds having activity at the CXCR4 receptor | ALLERGAN, INC. (US) | 2012-06-05 | — | — | US | disclosed |
| US-20090312305-A1 | BICYCLIC COMPOUNDS HAVING ACTIVITY AT THE CXCR4 RECEPTOR | ALLERGAN, INC. (US) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312305-A1 | BICYCLIC COMPOUNDS HAVING ACTIVITY AT THE CXCR4 RECEPTOR | CXCR4, CXCR2, CXCL12 | EHMT2 4669/4885HDAC1 614/4885HDAC6 688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.