Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23931262 | 1.00 | CHRM4 (0.51) | CHRM4CHRM5CHRM1CHRM3ATM | |
| SCHEMBL27038904 | 1.00 | CHRM4 (0.51) | CHRM4CHRM5CHRM1CHRM3ATM | |
| SCHEMBL3694182 | 0.89 | SMN1; SMN2 (0.61) | ATMSMN1; SMN2ALDH1A1CYP2D6POLB | |
| SCHEMBL28339538 | 0.89 | SMN1; SMN2 (0.61) | ATMSMN1; SMN2ALDH1A1CYP2D6POLB | |
| SCHEMBL2126340 | 0.88 | SCN1A (0.50) | CHRM4CHRM5CHRM1CHRM3ATM | |
| SCHEMBL23199841 | 0.83 | CHRM4 (0.54) | CHRM4CHRM5CHRM1CHRM3SMN1; SMN2 | |
| SCHEMBL21873695 | 0.83 | — | — | |
| SCHEMBL13841482 | 0.82 | CHRM1 (0.53) | CHRM4CHRM5CHRM1CHRM3SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL23199820 | 0.82 | SMN1; SMN2 (0.53) | CHRM4CHRM5CHRM1CHRM3ATM | |
| SCHEMBL13132381 | 0.82 | CHRM1 (0.53) | CHRM4CHRM5CHRM1CHRM3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312310-A1 | Imidazothiazole derivatives | TP53, MDM2, TP53BP1 | CHRM4 4178/4885CHRM5 4432/4885CHRM1 3151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.