SCHEMBL4201430

SCHEMBL4201430

C=CCOC(=O)OCCN1CCCC1=O

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
KMT2A Q03164 4/20 0.42
MEN1 O00255 2/20 0.42
TSHR P16473 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.37
PKM P14618 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
BLM P54132 1/20 0.35
PIK3CD O00329 1/20 0.35
HTT P42858 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11890778 0.88 TSHR (0.50) POLBKMT2AMEN1TSHRSMN1; SMN2
SCHEMBL11890787 0.84 POLB (0.41) POLBKMT2AMEN1TSHRSMN1; SMN2
SCHEMBL8219149 0.84 POLB (0.43) POLBKMT2AMEN1TSHRSMN1; SMN2
SCHEMBL18874629 0.82 POLB (0.44) POLBKMT2AMEN1TSHRSMN1; SMN2
SCHEMBL4193243 0.82 CYP3A4 (0.34) TSHRALDH1A1
SCHEMBL8059914 0.81 POLB (0.45) POLBKMT2AMEN1TSHRSMN1; SMN2
SCHEMBL10813947 0.81 KMT2A (0.47) POLBKMT2AMEN1TSHRSMN1; SMN2
SCHEMBL437536 0.81 POLB (0.45) POLBKMT2AMEN1TSHRSMN1; SMN2
SCHEMBL7999385 0.80 KMT2A (0.47) POLBKMT2AMEN1TSHRALDH1A1
SCHEMBL17387566 0.80 POLB (0.52) POLBKMT2AMEN1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1361246-B1 ORGANIC POLYMER AND NOVEL POLYMERIZABLE COMPOUND MITSUI CHEMICALS INC (JP) 2009-02-18 EP disclosed
US-6797805-B2 Organic polymers and novel polymerizable compounds MITSUI CHEMICALS, INC. (JP) 2004-09-28 US disclosed
EP-1361246-A1 ORGANIC POLYMER AND NOVEL POLYMERIZABLE COMPOUND Mitsui Chemicals, Inc. (JP) 2003-11-12 EP disclosed
US-20030166808-A1 Organic polymers and novel polymerizable compound MITSUI CHEMICALS, INC. (JP) 2003-09-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166808-A1 Organic polymers and novel polymerizable compound PCNA, UTP18, ODC1 POLB 188/4885KMT2A 2338/4885MEN1 3941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.