Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Tetradecanamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octadecanoic Acid Amide SCHEMBL27994152 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| SCHEMBL27595241 | 0.98 | SOAT1 (0.57) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL28029273 | 0.96 | SOAT1 (0.55) | SOAT1MEN1KMT2AFAAHTP53 | |
| Hydrochloric Acid SCHEMBL1705678 | 0.96 | SOAT1 (0.55) | SOAT1MEN1KMT2AFAAHTP53 | |
| Hydrochloric Acid SCHEMBL28807747 | 0.96 | SOAT1 (0.55) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL3831146 | 0.96 | SOAT1 (0.55) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL5346586 | 0.96 | SOAT1 (0.55) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL28799777 | 0.94 | SOAT1 (0.53) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL28243343 | 0.94 | SOAT1 (0.53) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL28169121 | 0.94 | SOAT1 (0.53) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1587553-B1 | QUATERNARY AMMONIUM ESTERS FOR DISINFECTION AND PRESERVATION | BAUSCH & LOMB (US) | 2009-03-11 | — | — | EP | disclosed |
| EP-1587553-A1 | QUATERNARY AMMONIUM ESTERS FOR DISINFECTION AND PRESERVATION | BAUSCH & LOMB INCORPORATED (US) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004054630-A1 | QUATERNARY AMMONIUM ESTERS FOR DISINFECTION AND PRESERVATION | BAUSCH & LOMB INCORPORATED (US) | 2004-07-01 | — | — | WO | disclosed |
| US-20040115160-A1 | Quaternary ammonium esters for disinfection and preservation | BAUSCH & LOMB INCORPORATED | 2004-06-17 | — | — | US | disclosed |