Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13190306 | 1.00 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL420310 | 1.00 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL422561 | 0.92 | HSP90AA1 (0.85) | HSP90AA1 | |
| SCHEMBL2693240 | 0.91 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL2693241 | 0.91 | HSP90AA1 (1.00) | HSP90AA1 | |
| SCHEMBL10215201 | 0.91 | HSP90AA1 (0.83) | HSP90AA1 | |
| SCHEMBL1394578 | 0.91 | HSP90AA1 (0.83) | HSP90AA1 | |
| SCHEMBL1394579 | 0.91 | HSP90AA1 (0.83) | HSP90AA1 | |
| SCHEMBL458829 | 0.89 | HSP90AA1 (0.84) | HSP90AA1 | |
| SCHEMBL13190077 | 0.89 | HSP90AA1 (0.84) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408762-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | SANOFI (FR) | 2012-01-25 | — | — | EP | claimed |
| WO-2010106290-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | SANOFI-AVENTIS (FR) | 2010-09-23 | — | — | WO | claimed |
| EP-2662367-B1 | NOVEL INDOLE OR INDAZOLE DERIVATIVE OR SALT THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2016-08-17 | — | — | EP | disclosed |
| US-9120780-B2 | Indole or indazole derivative or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-01 | — | — | US | disclosed |
| US-9120780-B2 | Indole or indazole derivative or salt thereof | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-01 | — | — | US | disclosed |
| EP-2662367-A1 | NOVEL INDOLE OR INDAZOLE DERIVATIVE OR SALT THEREOF | Taiho Pharmaceutical Co., Ltd. (JP) | 2013-11-13 | — | — | EP | disclosed |
| US-20130289072-A1 | NOVEL INDOLE OR INDAZOLE DERIVATIVE OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-31 | — | — | US | disclosed |
| US-20130289072-A1 | NOVEL INDOLE OR INDAZOLE DERIVATIVE OR SALT THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2013-10-31 | — | — | US | disclosed |
| EP-2408762-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | SANOFI (FR) | 2012-01-25 | — | — | EP | disclosed |
| US-20120010241-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | SANOFI (FR) | 2012-01-12 | — | — | US | disclosed |
| WO-2010106290-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | SANOFI-AVENTIS (FR) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010106290-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | SANOFI-AVENTIS (FR) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010241-A1 | HSP90 INHIBITING INDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING SAME AND USE THEREOF | HSP90AB2P, HSP90AB1, HSP90AA1 | HSP90AA1 3/4885 |
| US-20130289072-A1 | NOVEL INDOLE OR INDAZOLE DERIVATIVE OR SALT THEREOF | HSP90AB1, HSP90AA1, HSP90AB2P | HSP90AA1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.