SCHEMBL420440

SCHEMBL420440

ClC(Cl)(Cl)CCOCCC(Cl)(Cl)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148912 0.85
SCHEMBL1149089 0.85
SCHEMBL1149091 0.85
SCHEMBL1148915 0.85 TSHR (0.56)
SCHEMBL4398083 0.83
SCHEMBL1149071 0.81
SCHEMBL1148838 0.81
SCHEMBL1149070 0.81
SCHEMBL1148840 0.81
SCHEMBL6105996 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114755361-A Quality detection method of traditional Chinese medicine compound composition for treating allergic rhinitis of children 江苏省中医院 2022-07-15 CN claimed
CN-112843117-A Processing technology of honey-fried platycodon grandiflorum decoction pieces and quality standard research of honey-fried platycodon grandiflorum decoction pieces 内蒙古天奇中蒙制药股份有限公司 2021-05-28 CN claimed
CN-111721846-A Method for identifying traditional Chinese medicine preparation throat-clearing tablets 天津同仁堂集团股份有限公司 2020-09-29 CN claimed
US-20240182463-A1 SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG SHIONOGI & CO., LTD. (JP) 2024-06-06 US disclosed
CN-115902085-A Information spot thin-layer identification method for more than ten ingredients of agilawood medicinal material 河北省人民医院 2023-04-04 CN disclosed
CN-113509440-B Preparation method and stability improvement method of ketorolac multivesicular liposome with high encapsulation rate 中国药科大学 2022-08-30 CN disclosed
CN-113189261-B Platycodon grandiflorum detection method based on thin-layer chromatography 广州白云山中一药业有限公司 2022-08-16 CN disclosed
CN-114755361-A Quality detection method of traditional Chinese medicine compound composition for treating allergic rhinitis of children 江苏省中医院 2022-07-15 CN disclosed
CN-110002962-B Method for extracting alkyl resorcinol from wheat bran 南京财经大学 2022-07-12 CN disclosed
CN-114010700-A Preparation method and application of noninvasive dermal penetration technology transdermal absorbent containing traditional Chinese medicine effective components 哈尔滨职业技术学院 2022-02-08 CN disclosed
CN-113509440-A Preparation method and stability improvement method of ketorolac multivesicular liposome with high encapsulation rate 中国药科大学 2021-10-19 CN disclosed
US-4382889-A Epoxysuccinic acid derivatives TAISHO PHARMACEUTICAL CO., LTD. (JP) 1983-05-10 US disclosed
US-4333879-A CALCIUM-ACTIVATED NEUTRAL THIOLPROTEASE INHIBITOR USED IN THE TREATMENT OF MUSCULAR DYSTROPHY TAISHO PHARMACEUTICAL CO., LTD. (JP) 1982-06-08 US disclosed
US-4331802-A Organometallic reagents and their use in the synthesis of cardenolides and isocardenolides ADVANCE BIOFACTURES CORPORATION (US) 1982-05-25 US disclosed
US-4331697-A Novel heparin derivative, method for production thereof, and method for rendering biomedical materials antithrombotic by use of the novel heparin derivative TEIJIN LIMITED (JP) 1982-05-25 US disclosed
EP-0046828-A1 Heparin derivative, its production and methods for imparting antithrombotic activity to biomedical materials TEIJIN LIMITED (JP) 1982-03-10 EP disclosed
US-4185102-A SEDATIVES, TRANQUILIZERS, ANTICONVULSANTS ROUSSEL UCLAF (FR) 1980-01-22 US disclosed
US-4134976-A SEDATIVES, TRANQUILIZERS, ANTICONVULSANTS, HYPNOTICS, MUSCLE RELAXANTS ROUSSEL UCLAF (FR) 1979-01-16 US disclosed
US-4014892-A ANTHELMINTICS AMERICAN CYANAMID COMPANY (US) 1977-03-29 US disclosed
US-3989835-A Method of using 6-substituted amino phenyl-2,3,5,6-tetra-hydro[2,1-b]thiazoles for controlling gastrointestinal nematodes AMERICAN CYANAMID COMPANY (US) 1976-11-02 US disclosed