Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205111 | 1.00 | F10 (0.48) | F10PTGS2 | |
| SCHEMBL4215208 | 1.00 | F10 (0.48) | F10PTGS2 | |
| Hydrochloric Acid SCHEMBL4208890 | 0.99 | F10 (0.47) | F10PTGS2 | |
| SCHEMBL4206657 | 0.88 | F10 (0.48) | F10PTGS2 | |
| SCHEMBL4210268 | 0.83 | F10 (0.50) | F10PTGS2 | |
| SCHEMBL4206745 | 0.83 | F10 (0.50) | F10PTGS2 | |
| SCHEMBL77416 | 0.83 | JAK2 (0.53) | F10 | |
| SCHEMBL75782 | 0.83 | JAK2 (0.53) | F10 | |
| SCHEMBL75783 | 0.83 | JAK2 (0.53) | F10 | |
| Hydrochloric Acid SCHEMBL4202080 | 0.82 | F10 (0.49) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720844-B1 | PYRROLIDINO-1,2-DICARBOXY-1-(PHENYLAMIDE)-2-(4-(3-OXO-MORPHOLINO-4-YL)-PHENYLAMIDE) DERIVATIVES AND RELATED COMPOUNDS FOR USE AS INHIBITORS OF COAGULATION FACTOR XA IN THE TREATMENT OF THROMBO-EMBOLIC DISEASES | MERCK PATENT GMBH (DE) | 2009-04-29 | — | — | EP | claimed |
| EP-1720844-B1 | PYRROLIDINO-1,2-DICARBOXY-1-(PHENYLAMIDE)-2-(4-(3-OXO-MORPHOLINO-4-YL)-PHENYLAMIDE) DERIVATIVES AND RELATED COMPOUNDS FOR USE AS INHIBITORS OF COAGULATION FACTOR XA IN THE TREATMENT OF THROMBO-EMBOLIC DISEASES | MERCK PATENT GMBH (DE) | 2009-04-29 | — | — | EP | disclosed |