Threonine

Threonine

SCHEMBL4205142

CC(O)[C@H](N)C(=O)O.C[C@H](N)C(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.57
TP53 P04637 1/20 0.45
SLC1A3 P43003 3/20 0.42
SLC1A2 P43004 3/20 0.42
SLC1A1 P43005 2/20 0.42
USP2 O75604 1/20 0.39
SLCO1B1 Q9Y6L6 1/20 0.39
LTA4H P09960 1/20 0.34
GABRP O00591 3/20 0.33
GABRD O14764 3/20 0.33
GABRA1 P14867 3/20 0.33
GABRB1 P18505 3/20 0.33
GABRG2 P18507 3/20 0.33
GABRB3 P28472 3/20 0.33
GABRA5 P31644 3/20 0.33
GABRA3 P34903 3/20 0.33
GABRA2 P47869 3/20 0.33
GABRB2 P47870 3/20 0.33
GABRA4 P48169 3/20 0.33
GABRE P78334 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Threonine SCHEMBL1514133 1.00 SLC7A5 (0.57) SLC7A5TP53SLC1A3SLC1A2SLC1A1
Threonine SCHEMBL17113858 1.00 SLC7A5 (0.57) SLC7A5TP53SLC1A3SLC1A2SLC1A1
Threonine SCHEMBL16982373 1.00 SLC7A5 (0.57) SLC7A5TP53SLC1A3SLC1A2SLC1A1
Threonine SCHEMBL3209332 1.00 SLC7A5 (0.57) SLC7A5TP53SLC1A3SLC1A2SLC1A1
Threonine SCHEMBL1811514 1.00 SLC7A5 (0.57) SLC7A5TP53SLC1A3SLC1A2SLC1A1
Threonine SCHEMBL1811511 1.00 SLC7A5 (0.57) SLC7A5TP53SLC1A3SLC1A2SLC1A1
Threonine SCHEMBL27615994 0.95 SLC7A5 (0.52) SLC7A5TP53SLC1A3SLC1A2SLC1A1
Threonine SCHEMBL117301 0.94
Threonine SCHEMBL6038228 0.94 SLC7A5 (0.63) SLC7A5TP53SLC1A3SLC1A2SLC1A1
Threonine SCHEMBL14946556 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7618803-B2 Method for producing L-amino acid using bacteria belonging to the genus Escherichia AJINOMOTO CO., INC. (JP) 2009-11-17 US disclosed
US-7618804-B2 Method for producing L-amino acid using bacteria belonging to the genus Escherichia AJINOMOTO CO., INC. (JP) 2009-11-17 US disclosed
US-7476531-B2 Method for producing L-amino acid using bacteria belonging to the genus Escherichia AJINOMOTO CO., INC. (JP) 2009-01-13 US disclosed
US-20080261279-A1 METHOD FOR PRODUCING L-AMINO ACID USING BACTERIA BELONGING TO THE GENUS ESCHERICHIA TABOLINA EKATERINA ALEKSANDROV 2008-10-23 US disclosed
US-20080261278-A1 METHOD FOR PRODUCING L-AMINO ACID USING BACTERIA BELONGING TO THE GENUS ESCHERICHIA TABOLINA EKATERINA ALEKSANDROV 2008-10-23 US disclosed
EP-1526179-B9 Method for producing l-amino acid using bacteria belonging to the genus escherichia AJINOMOTO KK (JP) 2007-10-10 EP disclosed
EP-1526181-B1 Method for producing l-amino acid using bacteria belonging to the genus escherichia AJINOMOTO KK (JP) 2007-05-02 EP disclosed
EP-1526179-B1 Method for producing l-amino acid using bacteria belonging to the genus escherichia AJINOMOTO KK (JP) 2007-05-02 EP disclosed
EP-1239041-B1 Method for producing L-amino acid using bacteria belonging to the genus Escherichia AJINOMOTO KK (JP) 2006-04-19 EP disclosed
US-20050239175-A1 Method for producing L-amino acid using bacteria belonging to the genus Escherichia AJINOMOTO CO., INC. (JP) 2005-10-27 US disclosed
EP-1526181-A1 Method for producing l-amino acid using bacteria belonging to the genus escherichia Ajinomoto Co., Inc. (JP) 2005-04-27 EP disclosed
EP-1526179-A1 Method for producing l-amino acid using bacteria belonging to the genus escherichia Ajinomoto Co., Inc. (JP) 2005-04-27 EP disclosed
EP-0747395-B1 Composition for treating renal failure NESTLE SA (CH) 2003-05-02 EP disclosed
EP-1239041-A2 Method for producing L-amino acid using bacteria belonging to the genus Escherichia Ajinomoto Co., Inc. (JP) 2002-09-11 EP disclosed
US-5728678-A INCLUDING WHEY PROTEIN AND FREE AMINO ACIDS NESTEC LTD. (CH) 1998-03-17 US disclosed
EP-0747395-A1 Composition for treating renal failure CLINTEC NUTRITION COMPANY, AN ILLINOIS PARTNERSHIP (US) 1996-12-11 EP disclosed