Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK3 | O43781 | 4/20 | 0.54 |
| ▸ | GSK3B | P49841 | 4/20 | 0.49 |
| ▸ | CLK1 | P49759 | 2/20 | 0.49 |
| ▸ | CLK2 | P49760 | 2/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.49 |
| ▸ | CLK3 | P49761 | 1/20 | 0.49 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | DYRK4 | Q9NR20 | 1/20 | 0.49 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | GAK | O14976 | 1/20 | 0.47 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.47 |
| ▸ | STK10 | O94804 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13950941 | 1.00 | DYRK3 (0.54) | DYRK3GSK3BCLK1CLK2DYRK1A | |
| SCHEMBL4205344 | 1.00 | DYRK3 (0.54) | DYRK3GSK3BCLK1CLK2DYRK1A | |
| SCHEMBL4191921 | 0.83 | NPC1 (0.53) | DYRK3GSK3BCLK1CLK2DYRK1A | |
| SCHEMBL13950987 | 0.83 | NPC1 (0.53) | DYRK3GSK3BCLK1CLK2DYRK1A | |
| SCHEMBL4191920 | 0.83 | NPC1 (0.53) | DYRK3GSK3BCLK1CLK2DYRK1A | |
| SCHEMBL2789860 | 0.81 | DYRK3 (0.80) | DYRK3GSK3BCLK1CLK2DYRK1A | |
| SCHEMBL13196771 | 0.81 | DYRK3 (0.80) | DYRK3GSK3BCLK1CLK2DYRK1A | |
| SCHEMBL2789859 | 0.81 | DYRK3 (0.80) | DYRK3GSK3BCLK1CLK2DYRK1A | |
| SCHEMBL4201522 | 0.80 | PIM1 (0.71) | GSK3BCLK1CLK2DYRK1ACLK3 | |
| SCHEMBL4203735 | 0.80 | PIM1 (0.71) | GSK3BCLK1CLK2DYRK1ACLK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026345-A1 | THIAZOLIDINONE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | claimed |
| WO-2009026345-A1 | THIAZOLIDINONE COMPOUNDS, AND METHODS OF MAKING AND USING SAME | TARGEGEN INC. (US) | 2009-02-26 | — | — | WO | disclosed |