SCHEMBL4207168

SCHEMBL4207168

CCCO[Si](CCC)(NC1CCCC1)OCCC

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
EPHX1 P07099 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4207854 0.98 EPHX1 (0.35) CYP1A2CYP2D6CYP2C19EPHX1KDM4E
SCHEMBL4205780 0.89 MEN1 (0.37) CYP1A2CYP2D6CYP2C19EPHX1MEN1
SCHEMBL4208598 0.88 EPHX1 (0.37) EPHX1MEN1KMT2A
SCHEMBL4207926 0.87 EPHX1 (0.33) CYP1A2CYP2D6CYP2C19EPHX1KDM4E
SCHEMBL4207846 0.87 CYP1A2 (0.37) CYP1A2CYP2D6CYP2C19EPHX1KDM4E
SCHEMBL4213099 0.85 CYP1A2 (0.36) CYP1A2CYP2D6CYP2C19EPHX1KDM4E
SCHEMBL4207124 0.85 EPHX1 (0.36) EPHX1KDM4EALDH1A1MEN1KMT2A
SCHEMBL4207177 0.81 EPHX1 (0.34) CYP1A2CYP2D6CYP2C19EPHX1KDM4E
SCHEMBL4207361 0.80 POLB (0.35)
SCHEMBL1536148 0.79 EPHX1 (0.37) EPHX1KDM4EALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090253873-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME TOHO CATALYST CO., LTD (JP) 2009-10-08 US disclosed
EP-1829898-A1 SOLID CATALYST COMPONENT AND CATALYST FOR POLYMERIZATION OF OLEFIN, AND METHOD FOR PRODUCING POLYMER OR COPOLYMER OF OLEFIN USING THE SAME Toho Catalyst Co., Ltd. (JP) 2007-09-05 EP disclosed