Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 5/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.71 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.71 |
| ▸ | PTGIR | P43119 | 5/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797653 | 0.86 | PTGS1 (0.74) | ABCB1PTGS1PTGS2AKR1C3AKR1C2 | |
| Acetic Acid SCHEMBL6025717 | 0.84 | PTGS1 (0.71) | ABCB1PTGS1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL2237296 | 0.83 | ABCB1 (1.00) | ABCB1PTGS1PTGS2AKR1C3AKR1C2 | |
| SCHEMBL4211502 | 0.82 | ABCB1 (0.76) | ABCB1PTGS1PTGS2PTGIRAKR1C3 | |
| SCHEMBL14280740 | 0.82 | ABCB1 (0.80) | ABCB1PTGS1PTGS2PTGIRAKR1C3 | |
| SCHEMBL13802379 | 0.81 | ABCB1 (0.60) | ABCB1PTGS1PTGS2PTGIRAKR1C3 | |
| SCHEMBL13802389 | 0.81 | ABCB1 (0.70) | ABCB1PTGS1PTGS2PTGIRAKR1C3 | |
| SCHEMBL13802412 | 0.80 | ABCB1 (0.65) | ABCB1PTGS1PTGS2PTGIRAKR1C3 | |
| SCHEMBL13802388 | 0.80 | ABCB1 (0.76) | ABCB1PTGS1PTGS2PTGIRAKR1C3 | |
| SCHEMBL13802378 | 0.80 | ABCB1 (0.75) | ABCB1PTGS1PTGS2PTGIRAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | ABCB1 139/4885PTGS1 2198/4885PTGS2 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.