⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795029 | 1.00 | MEN1 (0.52) | — | |
| SCHEMBL1797937 | 0.97 | — | — | |
| SCHEMBL732356 | 0.87 | — | — | |
| SCHEMBL16566360 | 0.77 | — | — | |
| SCHEMBL9206028 | 0.76 | TSHR (0.61) | — | |
| SCHEMBL7697182 | 0.76 | TSHR (0.61) | — | |
| SCHEMBL4389498 | 0.76 | TSHR (0.61) | — | |
| SCHEMBL277225 | 0.76 | TSHR (0.61) | — | |
| SCHEMBL4399689 | 0.76 | TSHR (0.61) | — | |
| SCHEMBL7699808 | 0.76 | TSHR (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434354-B1 | SEPARATION MATERIAL FOR BLOOD COAGULATION FACTOR, PREPARATION AND USE THEREOF | KURITA WATER INDUSTRIES LTD. (JP) | 1993-08-11 | — | — | EP | claimed |
| US-5096593-A | SEPARATION MATERIAL DERIVED FROM GLUCOMANNAN FOR BLOOD COAGULATION FACTOR, PREPARATION AND USE THEREOF | KURITA WATER INDUSTRIES LTD. (JP) | 1992-03-17 | — | — | US | claimed |
| US-20240158421-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2024-05-16 | — | — | US | disclosed |
| US-11691995-B2 | Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2023-07-04 | — | — | US | disclosed |
| US-20220024921-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND PHARMACEUTICAL | NIPPON SHINYAKU CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| EP-3882239-A1 | 1,3,4-OXADIAZOLONE COMPOUND AND MEDICINE | Nippon Shinyaku Co., Ltd. (JP) | 2021-09-22 | — | — | EP | disclosed |
| CN-113302184-A | 1,3, 4-oxadiazolinone compounds and drugs | 日本新药株式会社 | 2021-08-24 | — | — | CN | disclosed |
| CN-107454900-B | Novel imidazo [1,2-A ] quinoxalines and derivatives thereof for the treatment of cancer | 蒙彼利埃大学 | 2020-08-07 | — | — | CN | disclosed |
| US-10689384-B2 | Imidazo[1,2-a]quinoxalines and derivatives thereof for the treatment of cancer | UNIVERSITE DE MONTPELLIER (FR) | 2020-06-23 | — | — | US | disclosed |
| EP-3556401-A1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | The University of North Carolina at Chapel Hill (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-2669269-B1 | NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS | UNIV NORTH CAROLINA CHAPEL HILL (US) | 2019-05-22 | — | — | EP | disclosed |
| US-6495542-B1 | SUCH AS 2-METHOXY-N-(2-METHYL-1H-BENZIMIDAZOL-4-YL)-4-(2,3,4,5-TETRAHYDRO-5-OXO-1H-1-BENZAZEPIN-1-YL)CARBONYL-BENZAM IDE; HYPERTENSION, HEART FAILURE, RENAL INSUFFICIENCY, EDEMA, ASCITES, VASOPRESSIN PARASECRETION SYNDROME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1051415-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037637-A1 | BENZAMIDE DERIVATIVES AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-07-29 | — | — | WO | disclosed |
| US-5646154-A | Pharmaceutical compositions for inhibiting the formation of tumor necrosis factor | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1997-07-08 | — | — | US | disclosed |
| EP-0664128-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING TUMOR NECROSIS FACTOR PRODUCTION | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1995-07-26 | — | — | EP | disclosed |
| EP-0434354-B1 | SEPARATION MATERIAL FOR BLOOD COAGULATION FACTOR, PREPARATION AND USE THEREOF | KURITA WATER INDUSTRIES LTD. (JP) | 1993-08-11 | — | — | EP | disclosed |
| US-5096593-A | SEPARATION MATERIAL DERIVED FROM GLUCOMANNAN FOR BLOOD COAGULATION FACTOR, PREPARATION AND USE THEREOF | KURITA WATER INDUSTRIES LTD. (JP) | 1992-03-17 | — | — | US | disclosed |
| EP-0434354-A1 | Separation material for blood coagulation factor, preparation and use thereof | KURITA WATER INDUSTRIES LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |
| EP-0407816-A2 | Base modified nucleosides | ABBOTT LABORATORIES (US) | 1991-01-16 | — | — | EP | disclosed |