SCHEMBL421508

SCHEMBL421508

FC(F)(F)[N]C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5605455 0.94
SCHEMBL7110900 0.94
SCHEMBL1705444 0.62
SCHEMBL687303 0.59
SCHEMBL12655284 0.59
SCHEMBL29143143 0.59
SCHEMBL492494 0.59
SCHEMBL9174626 0.59
SCHEMBL9174636 0.59
SCHEMBL20421268 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2867019-B1 SLIDE BEARING COMPRISING A PRIMER SYSTEM AS ADHESION PROMOTER SAINT GOBAIN PERFORMANCE PLASTICS PAMPUS GMBH (DE) 2023-01-18 EP claimed
US-10563696-B2 Slide bearing comprising a primer system as adhesion promoter SAINT-GOBAIN PERFORMANCE PLASTICS PAMPUS GMBH (DE) 2020-02-18 US claimed
US-20190053492-A1 SUBSTITUTED PYRIDINE COMPOUNDS AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2019-02-21 US claimed
US-20190024714-A1 SLIDE BEARING COMPRISING A PRIMER SYSTEM AS ADHESION PROMOTER SAINT GOBAIN PERFORMANCE PLASTICS PAMPUS GMBH (DE) 2019-01-24 US claimed
US-10113588-B2 Slide bearing comprising a primer system as adhesion promoter SAINT-GOBAIN PERFORMANCE PLASTICS PAMPUS GMBH (DE) 2018-10-30 US claimed
US-20160238072-A1 SLIDE BEARING COMPRISING A PRIMER SYSTEM AS ADHESION PROMOTER SAINT-GOBAIN PERFORMANCE PLASTICS PAMPUS GMBH (DE) 2016-08-18 US claimed
EP-2867019-A1 SLIDE BEARING COMPRISING A PRIMER SYSTEM AS ADHESION PROMOTER Saint-Gobain Performance Plastics Pampus GmbH (DE) 2015-05-06 EP claimed
WO-2014001524-A1 SLIDE BEARING COMPRISING A PRIMER SYSTEM AS ADHESION PROMOTER SAINT-GOBAIN PERFORMANCE PLASTICS PAMPUS GMBH (DE) 2014-01-03 WO claimed
US-8188055-B2 Inactivators of O6-alkylguanine-DNA alkyltransferase THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2012-05-29 US claimed
US-7825096-B2 O6-alkylguanine-DNA alkyltransferase inactivators and beta-glucuronidase cleavable prodrugs THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2010-11-02 US claimed
EP-1142893-A1 Substituted O6-benzylguanines and 6(4)-benzyloxypyrimidines THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) 2001-10-10 EP claimed
US-5958932-A ANTITUMOR AGENT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1999-09-28 US claimed
US-5753668-A Substituted benzyloxypyrimidines and their inactivation of O6 -alkylguanine-DNA alkyltransferase THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1998-05-19 US claimed
EP-0775142-A1 SUBSTITUTED O6 -BENZYLGUANINES AND 6(4)-BENZYLOXYPYRIMIDINES THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services (US) 1997-05-28 EP claimed
US-5525606-A CHEMOTHERAPEUTIC ANTITUMOR AGENT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-06-11 US claimed
WO-1996004281-A1 SUBSTITUTED O6-BENZYLGUANINES AND 6(4)-BENZYLOXYPYRIMIDINES THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-02-15 WO claimed
EP-0456226-B1 Dye forming coupler and silver halide color photographic material containing the same and method for forming color image FUJI PHOTO FILM CO LTD (JP) 1994-09-07 EP claimed
US-5164289-A Cyan coupler with no absorption in the blue or green, heat and light stable FUJI PHOTO FILM CO., LTD. (JP) 1992-11-17 US claimed
EP-0456226-A1 Dye forming coupler and silver halide color photographic material containing the same and method for forming color image FUJI PHOTO FILM CO., LTD. (JP) 1991-11-13 EP claimed
EP-0048850-A1 1-Benzotriazolyloxy-acetic-acid amides, process for their preparation and their use as herbicides BAYER AG (DE) 1982-04-07 EP claimed