SCHEMBL42179

SCHEMBL42179

Cc1ccc(C[C@@H](C)N)cc1

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.64
SLC6A2 P23975 5/20 0.64
SLC6A3 Q01959 3/20 0.64
SLC6A4 P31645 4/20 0.62
MAOA P21397 2/20 0.62
SIGMAR1 Q99720 1/20 0.62
CYP2A6 P11509 1/20 0.62
ADORA2A P29274 1/20 0.62
ADORA1 P30542 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81938 1.00 TAAR1 (0.64) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL22873938 1.00 TAAR1 (0.64) TAAR1SLC6A2SLC6A3SLC6A4MAOA
Hydrochloric Acid SCHEMBL15204356 0.98 TAAR1 (0.61) TAAR1SLC6A2SLC6A3SLC6A4MAOA
Hydrochloric Acid SCHEMBL28093667 0.95 TAAR1 (0.59) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL9467782 0.93 TAAR1 (0.57) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL10872752 0.89 TAAR1 (0.76) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL10872755 0.89 TAAR1 (0.76) TAAR1SLC6A2SLC6A3SLC6A4MAOA
SCHEMBL24017123 0.82 TAAR1 (0.48) TAAR1SLC6A2SLC6A3SLC6A4CYP2A6
SCHEMBL22013359 0.82 TAAR1 (0.48) TAAR1SLC6A2SLC6A3SLC6A4CYP2A6
SCHEMBL24017125 0.82 TAAR1 (0.48) TAAR1SLC6A2SLC6A3SLC6A4CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 521 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117871845-A Kit for detecting methyl amphetamine and preparation method thereof 北京迈康源生物科技有限公司 2024-04-12 CN claimed
CN-116710084-A Use of mGluR5 antagonists for the treatment of amphetamine addiction 诺华股份有限公司 2023-09-05 CN claimed
CN-116606638-A Preparation method and application of water-soluble quantum dot 广纳达康(广州)生物科技有限公司 2023-08-18 CN claimed
CN-109752536-B Optical probe based on gold nanoparticle efficient assembly structure and preparation and application thereof 浙江工业大学 2022-03-15 CN claimed
CN-111363011-B Methamphetamine vaccine and preparation method and application thereof 北京大学 2021-08-24 CN claimed
CN-111363011-A Methamphetamine vaccine and preparation method and application thereof 北京大学 2020-07-03 CN claimed
CN-105555763-A Indole-carboxamide derivatives HOFFMANN LA ROCHE 2016-05-04 CN claimed
CN-105473568-A 1, 7-naphthyridine derivatives HOFFMANN LA ROCHE 2016-04-06 CN claimed
CN-105473545-A Dihydroxyphenyl neurotransmitter compounds, compositions, and methods AUSPEX PHARMACEUTICALS INC 2016-04-06 CN claimed
CN-105367647-A Preparation method of methamphetamine artificial antigen ABON BIOPHARM (HANGZHOU) CO LTD 2016-03-02 CN claimed
EP-2038660-A2 A METHOD FOR THE PRESUMPTIVE DETECTION OF SUBSTANCES HERIOT-WATT UNIVERSITY (GB) 2009-03-25 EP claimed
CN-101119963-A Methamphetamine derivatives and conjugates for use in immunoassays HOFFMANN LA ROCHE (CH) 2008-02-06 CN claimed
WO-2008001116-A2 A METHOD FOR THE PRESUMPTIVE DETECTION OF SUBSTANCES HERIOT-WATT UNIVERSITY (GB) 2008-01-03 WO claimed
CN-101061091-A Method for purifying benzphetamine hydrochloride MALLINCKRODT INC (US) 2007-10-24 CN claimed
CN-1313434-C Darr reaction process of quinone derivative composition to produce free radical and its application SHANDONG PROVINCIAL RES CT FOR (CN) 2007-05-02 CN claimed
CN-1898201-A Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents SENTION INC (US) 2007-01-17 CN claimed
CN-1526695-A Darr reaction process of quinone derivative composition to produce free radical and its application 山东省生物信息工程技术研究中心 2004-09-08 CN claimed
CN-1124341-C Monoclonal antibody specific for methamphetamine, hybridoma producing the same, kit containing the same and use thereof BIOTECHNOLOGY DEV CT (CN) 2003-10-15 CN claimed
EP-0897540-B1 METHOD FOR DETECTING AND/OR QUANTIFYING A HAPTEN IN A HOMOGENEOUS PHASE AND DEVICE FOR IMPLEMENTATION THEREOF WALLONE REGION (BE) 2001-07-04 EP claimed
CN-1179469-A Monoclonal antibody specific for methamphetamine, hybridoma producing the same, kit containing the same and use thereof BIOTECHNOLOGY DEV CENTER (CN) 1998-04-22 CN claimed