Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13748834 | 0.86 | MCHR1 (0.62) | MCHR1 | |
| SCHEMBL1365708 | 0.85 | MCHR1 (0.56) | MCHR1ESR1ESR2 | |
| SCHEMBL4538551 | 0.85 | MCHR1 (0.49) | MCHR1ESR1ESR2 | |
| SCHEMBL4046311 | 0.81 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL1364958 | 0.80 | MCHR1 (0.58) | MCHR1 | |
| SCHEMBL1365157 | 0.79 | MCHR1 (0.57) | MCHR1 | |
| SCHEMBL13748123 | 0.79 | MCHR1 (0.53) | MCHR1 | |
| SCHEMBL1367199 | 0.78 | MCHR1 (0.64) | MCHR1 | |
| SCHEMBL10265276 | 0.78 | ESR1 (0.47) | ESR1ESR2 | |
| SCHEMBL13748154 | 0.77 | MCHR1 (0.49) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |