Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | HTR1D | P28221 | 1/20 | 0.59 |
| ▸ | HTR1B | P28222 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | HTR1E | P28566 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | HTR7 | P34969 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | HTR6 | P50406 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27094892 | 0.85 | KDM4E (0.62) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL420346 | 0.84 | HTR2C (0.64) | HTR2AHTR1AHTR1DHTR1BHTR2C | |
| SCHEMBL9217751 | 0.82 | KDM4E (0.60) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL28564728 | 0.81 | KDM4E (0.59) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL28564727 | 0.81 | KDM4E (0.59) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL8999204 | 0.80 | KDM4E (0.66) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL27835748 | 0.80 | KDM4E (0.58) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL22607730 | 0.80 | KDM4E (0.56) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| Acetic Acid SCHEMBL264322 | 0.80 | HTR2A (0.82) | HTR2AADRB1HTR1AADRA2ASLC6A2 | |
| SCHEMBL10030545 | 0.78 | KDM4E (0.76) | HTR2AADRB1HTR1AADRA2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | HENKEL AG & CO. KGAA (DE) | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120060856-A1 | Cosmetic Composition and Reshaping Method for Keratinic Fibers | H1-0, H1-3, H1-2 | HTR2A 2105/4885ADRB1 4340/4885HTR1A 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.