Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 17/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3234560 | 0.91 | UTS2R (0.43) | UTS2RROCK2ROCK1 | |
| SCHEMBL4227998 | 0.90 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL3233800 | 0.89 | UTS2R (0.46) | UTS2RROCK2ROCK1 | |
| SCHEMBL3225551 | 0.88 | UTS2R (0.41) | UTS2RROCK2ROCK1ALDH1A1 | |
| SCHEMBL4232522 | 0.87 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL4224427 | 0.87 | UTS2R (0.40) | UTS2RROCK2ROCK1SMN1; SMN2 | |
| SCHEMBL3232007 | 0.87 | UTS2R (0.45) | UTS2RROCK2ROCK1 | |
| SCHEMBL4219227 | 0.86 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| SCHEMBL4228771 | 0.86 | UTS2R (0.44) | UTS2RROCK2ROCK1 | |
| SCHEMBL4225350 | 0.86 | UTS2R (0.42) | UTS2RROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2135620-A1 | OCULAR HYPOTENSIVE AGENT COMPRISING COMPOUND CAPABLE OF INHIBITING HISTONE DEACETYLASE AS ACTIVE INGREDIENT | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-23 | — | — | EP | disclosed |
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |