⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399222 | 0.76 | — | — | |
| SCHEMBL8385079 | 0.67 | — | — | |
| SCHEMBL537131 | 0.65 | — | — | |
| SCHEMBL8737029 | 0.65 | — | — | |
| SCHEMBL6566354 | 0.64 | — | — | |
| SCHEMBL732285 | 0.59 | — | — | |
| SCHEMBL6950949 | 0.57 | — | — | |
| SCHEMBL6315838 | 0.57 | — | — | |
| SCHEMBL2370989 | 0.57 | — | — | |
| SCHEMBL6316403 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530298-A | A kind of synthetic method of intermediate 2,2- dinethyl cyclopropane carboxylic acid methyl esters | 徐州诺克非医药科技有限公司 | 2018-09-14 | — | — | CN | disclosed |
| US-8815350-B2 | Method for grafting a porous element for leucodepletion | MACO PHARMA SOCIETE ANONYME (FR) | 2014-08-26 | — | — | US | disclosed |
| US-20090159522-A1 | METHOD FOR GRAFTING A POROUS ELEMENT FOR LEUCODEPLETION | MACO PHARMA SOCIETE ANONYME (FR) | 2009-06-25 | — | — | US | disclosed |
| CN-1303374-A | Substituted indolinones, process for their preparation and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA (DE) | 2001-07-11 | — | — | CN | disclosed |