⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21483385 | 0.76 | — | — | |
| SCHEMBL16945613 | 0.76 | — | — | |
| SCHEMBL4842013 | 0.73 | TSHR (0.37) | — | |
| SCHEMBL20402406 | 0.72 | — | — | |
| SCHEMBL16945615 | 0.72 | — | — | |
| SCHEMBL16945636 | 0.72 | — | — | |
| SCHEMBL6221976 | 0.71 | HPGD (0.47) | — | |
| SCHEMBL8362604 | 0.71 | — | — | |
| SCHEMBL24952665 | 0.69 | — | — | |
| SCHEMBL3594955 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240050578-A1 | BI-FUNCTIONAL MOLECULES TO DEGRADE CIRCULATING PROTEINS | UNIV YALE (US) | 2024-02-15 | — | — | US | claimed |
| US-11767301-B2 | Bi-functional molecules to degrade circulating proteins | YALE UNIVERSITY (US) | 2023-09-26 | — | — | US | claimed |
| US-20230233689-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | UNIV YALE (US) | 2023-07-27 | — | — | US | claimed |
| US-20230159611-A1 | SMALL MOLECULE ADAPTER REGULATED, TARGET SPECIFIC CHIMERIC ANTIGEN RECEPTOR BEARING T CELLS (SMART CARS) | YALE UNIVERSITY | 2023-05-25 | — | — | US | claimed |
| US-20230097887-A1 | Bi-functional Molecules to Degrade Circulating Proteins | YALE UNIVERSITY | 2023-03-30 | — | — | US | claimed |
| US-20230083388-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | UNIV YALE (US) | 2023-03-16 | — | — | US | claimed |
| US-20210145974-A1 | Bifunctional Small Molecules to Target the Selective Degradation of Circulating Proteins | YALE UNIVERSITY | 2021-05-20 | — | — | US | claimed |
| US-20210139436-A1 | Bi-functional Molecules to Degrade Circulating Proteins | YALE UNIVERSITY | 2021-05-13 | — | — | US | claimed |
| US-10961527-B2 | Reprogramming urokinase into an antibody-recruiting anticancer agent | YALE UNIVERSITY (US) | 2021-03-30 | — | — | US | claimed |
| EP-3773727-A1 | BIFUNCTIONAL SMALL MOLECULES TO TARGET THE SELECTIVE DEGRADATION OF CIRCULATING PROTEINS | Yale University (US) | 2021-02-17 | — | — | EP | claimed |
| WO-2017053776-A1 | THE TOTAL SYNTHESIS OF GLUCOSEPANE AND COMPOUNDS OBTAINED THEREFROM | YALE UNIVERSITY (US) | 2017-03-30 | — | — | WO | claimed |
| WO-2017023994-A1 | SMALL MOLECULE BASED ANTIBODY-RECRUITING COMPOUNDS FOR CANCER TREATMENT | YALE UNIVERSITY (US) | 2017-02-09 | — | — | WO | claimed |
| US-9556167-B2 | TLR-agonist-conjugated antibody recruiting molecules (TLR-ARMs) | YALE UNIVERSITY (US) | 2017-01-31 | — | — | US | claimed |
| US-20150110742-A1 | TLR-AGONIST-CONJUGATED ANTIBODY RECRUITING MOLECULES (TLR-ARMS) | YALE UNIVERSITY (US) | 2015-04-23 | — | — | US | claimed |
| WO-2013166110-A1 | TLR-AGONIST-CONJUGATED ANTIBODY RECRUITING MOLECULES (TLR_ARMS) | YALE UNIVERSITY (US) | 2013-11-07 | — | — | WO | claimed |
| EP-1408986-A4 | PROTEOMIMETIC COMPOUNDS AND METHODS | UNIV YALE (US) | 2006-01-11 | — | — | EP | claimed |
| US-20050215563-A1 | Proteomimetic compounds and methods | YALE UNIVERSITY | 2005-09-29 | — | — | US | claimed |
| EP-1408986-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2004-04-21 | — | — | EP | claimed |
| US-20030008882-A1 | Proteomimetic compounds and methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-01-09 | — | — | US | claimed |
| WO-2002089738-A2 | PROTEOMIMETIC COMPOUNDS AND METHODS | YALE UNIVERSITY (US) | 2002-11-14 | — | — | WO | claimed |