SCHEMBL422430

SCHEMBL422430

C=CC(=O)O[PH](=O)OCN

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.34
ALDH1A1 P00352 4/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 2/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1885673 0.79 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27483723 0.79 TSHR (0.39) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27702917 0.78 TSHR (0.52) TSHRALDH1A1TP53HIF1ACYP3A4
Trimethylammonium SCHEMBL27841633 0.75 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29080623 0.72 CHRM5 (0.37) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL27548215 0.71
SCHEMBL28177375 0.71 TSHR (0.49) TSHRALDH1A1CYP3A4HPGD
SCHEMBL28127558 0.71 TSHR (0.49) TSHRALDH1A1CYP3A4HPGD
SCHEMBL29004766 0.70
SCHEMBL14989067 0.70 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11504452-B2 Ceramic particle composite material SOFSERA CORPORATION (JP) 2022-11-22 US disclosed
US-11168031-B2 Calcium phosphate sintered particles and production method therefor SOFSERA CORPORATION (JP) 2021-11-09 US disclosed
US-20200181026-A1 CALCIUM PHOSPHATE SINTERED BODY PARTICLES AND METHOD FOR PRODUCING SAME SOFSERA CORPORATION (JP) 2020-06-11 US disclosed
US-20190290807-A1 CERAMIC PARTICLE CARRYING STENT SOFSERA CORPORATION (JP) 2019-09-26 US disclosed
US-20190262508-A1 NOVEL CERAMIC PARTICLE COMPOSITE MATERIAL SOFSERA CORPORATION (JP) 2019-08-29 US disclosed
EP-3508229-A1 CERAMIC PARTICLE CARRYING STENT SofSera Corporation (JP) 2019-07-10 EP disclosed
EP-3508225-A1 NOVEL CERAMIC PARTICLE COMPOSITE MATERIAL SofSera Corporation (JP) 2019-07-10 EP disclosed
EP-3508462-A1 CALCIUM PHOSPHATE SINTERED PARTICLES AND PRODUCTION METHOD THEREFOR SofSera Corporation (JP) 2019-07-10 EP disclosed
EP-3508228-A1 CERAMIC PARTICLE CARRYING MEDICAL TUBE AND/OR CUFF SofSera Corporation (JP) 2019-07-10 EP disclosed
EP-3480166-A1 CALCIUM PHOSPHATE SINTERED BODY PARTICLES AND METHOD FOR PRODUCING SAME Sofsera Corporation (JP) 2019-05-08 EP disclosed
US-20170087060-A1 TOOTH SURFACE REPAIRING MATERIAL SOFSERA CORPORATION (JP) 2017-03-30 US disclosed
US-20120064343-A1 TOOTH SURFACE REPAIRING MATERIAL SOFSERA CORPORATION (JP) 2012-03-15 US disclosed
EP-2409677-A1 TOOTH SURFACE REPAIRING MATERIAL Southcoast Dental Co., Ltd. (JP) 2012-01-25 EP disclosed