SCHEMBL42267

SCHEMBL42267

CCCCC1CC[CH]CC1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.58
MAPK1 P28482 2/20 0.42
HTT P42858 2/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.36
POLB P06746 1/20 0.36
HRH3 Q9Y5N1 1/20 0.34
NOS1 P29475 2/20 0.33
NOS2 P35228 2/20 0.33
EPHX1 P07099 1/20 0.32
CHRM1 P11229 2/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32
CHRM5 P08912 1/20 0.32
ADRA2A P08913 1/20 0.32
DRD2 P14416 1/20 0.32
ADRA2B P18089 1/20 0.32
CHRM3 P20309 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27288023 0.98 CYP1A2 (0.56) CYP1A2MAPK1HTTLMNAMAPT
SCHEMBL548259 0.93 CYP1A2 (0.50) CYP1A2MAPK1HTTLMNAMAPT
SCHEMBL144946 0.91 CYP1A2 (0.61) CYP1A2MAPK1HTTLMNAMAPT
SCHEMBL55638 0.91 CYP1A2 (0.48) CYP1A2MAPK1HTTLMNAMAPT
SCHEMBL4923265 0.91 CYP1A2 (0.48) CYP1A2MAPK1HTTLMNAMAPT
SCHEMBL8744097 0.91 CYP1A2 (0.48) CYP1A2MAPK1HTTLMNAMAPT
SCHEMBL4921924 0.91 CYP1A2 (0.48) CYP1A2MAPK1HTTLMNAMAPT
SCHEMBL547742 0.91 CYP1A2 (0.48) CYP1A2MAPK1HTTLMNAMAPT
SCHEMBL4921810 0.91 CYP1A2 (0.48) CYP1A2MAPK1HTTLMNAMAPT
SCHEMBL1127668 0.91 CYP1A2 (0.48) CYP1A2MAPK1HTTLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2944 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347597-A1 PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS Otsuka Pharmaceutical Co., Ltd. (JP) 2024-04-10 EP claimed
CN-117510421-B Fluorine-containing benzotriazolyl fluorescent compound for optical transfer film and synthesis method thereof 河北美星化工有限公司 2024-04-05 CN claimed
CN-117510421-A Fluorine-containing benzotriazolyl fluorescent compound for optical transfer film and synthesis method thereof 河北美星化工有限公司 2024-02-06 CN claimed
CN-117377674-A Pyrazolo [1,5-a ] pyrimidine compounds for the treatment of dermatological disorders 大塚制药株式会社 2024-01-09 CN claimed
WO-2022255408-A1 PYRAZOLO[1,5-A]PYRIMIDINE COMPOUND FOR THE TREATMENT OF DERMAL DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2022-12-08 WO claimed
EP-3148969-B1 COMPOUNDS FOR THE TREATMENT OF SEIZURES AND OTHER CENTRAL NERVOUS SYSTEM DISORDERS AND CONDITIONS KETOGEN INC (CA) 2020-11-11 EP claimed
EP-2760899-B1 COATING COMPOSITION AND USE THEREOF PPG EUROPE B V (NL) 2020-08-19 EP claimed
CN-111533764-A Method for preparing siloxyindene derivative by using domino reaction 杭州师范大学 2020-08-14 CN claimed
US-10550275-B2 UV-LED curable clear ink composition for ink jet printing SAKATA INX CORP. (JP) 2020-02-04 US claimed
CN-110423016-A A kind of preparation method of extinction anti-glare glass HEYUAN CITY ORIENTAL SILICON SOURCE TECH CO LTD 2019-11-08 CN claimed
US-4968676-A PLANTS, SOILS, SEEDS BASF AKTIENGESELLSCHAFT (DE) 1990-11-06 US claimed
US-4897425-A Fungicidal cyclohexylamines BASF AKTIENGESELLSCHAFT (DE) 1990-01-30 US claimed
EP-0194525-B1 N-CARBAMOYL-AZOLES AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1988-08-10 EP claimed
US-4631328-A LIQUID CRYSTALS BASF AKTIENGESELLSCHAFT (DE) 1986-12-23 US claimed
EP-0194525-A2 N-Carbamoyl-azoles and fungicides containing them BASF Aktiengesellschaft (DE) 1986-09-17 EP claimed
EP-0172962-A1 Prostaglandins ONO PHARMACEUTICAL CO., LTD. (JP) 1986-03-05 EP claimed
US-4562204-A ANTITUMOR, ANTILEUKEMIA AGENT ONO PHARMACEUTICAL CO., LTD. (JP) 1985-12-31 US claimed
EP-0099672-A2 Trans-Delta 2-prostaglandin D derivatives, process for their preparation and compositions containing them ONO PHARMACEUTICAL CO., LTD. (JP) 1984-02-01 EP claimed
EP-0097023-A2 Prostaglandin D derivatives, process for their preparation and compositions containing them ONO PHARMACEUTICAL CO., LTD. (JP) 1983-12-28 EP claimed
EP-0033947-B1 LIQUID CRYSTAL DISPLAY ELEMENT KABUSHIKI KAISHA TOSHIBA (JP) 1983-09-21 EP claimed