Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 14/20 | 0.49 |
| ▸ | KDM1A | O60341 | 5/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 5/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.43 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3772515 | 0.96 | EHMT2 (0.53) | EHMT2KDM1ARCOR1APPNSD2 | |
| SCHEMBL4230308 | 0.93 | APP (0.48) | EHMT2KDM1ARCOR1APPNSD2 | |
| SCHEMBL4234177 | 0.90 | EHMT2 (0.51) | EHMT2KDM1ARCOR1APPNSD2 | |
| SCHEMBL4230764 | 0.89 | TLR7 (0.58) | EHMT2KDM1ARCOR1APPNSD2 | |
| SCHEMBL3777259 | 0.88 | EHMT2 (0.51) | EHMT2KDM1ARCOR1APPNSD2 | |
| SCHEMBL3775638 | 0.87 | SSTR5 (0.55) | EHMT2KDM1ARCOR1APPNSD2 | |
| SCHEMBL4231381 | 0.86 | EHMT2 (0.52) | EHMT2KDM1ARCOR1APPNSD2 | |
| SCHEMBL3775880 | 0.86 | SSTR5 (0.57) | EHMT2KDM1ARCOR1APPNSD2 | |
| SCHEMBL3774437 | 0.85 | EHMT2 (0.55) | EHMT2KDM1ARCOR1APPNSD2 | |
| SCHEMBL3781568 | 0.85 | SSTR5 (0.57) | EHMT2KDM1ARCOR1APPNSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001867-B1 | PYRIMIDINE, QUINAZOLINE, PTERIDINE AND TRIAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2009-07-01 | — | — | EP | disclosed |