Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 6/20 | 0.48 |
| ▸ | MEF2D | Q14814 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4231224 | 0.95 | HDAC4 (0.47) | HDAC4MEF2DHDAC1HDAC3HDAC2 | |
| SCHEMBL2470981 | 0.90 | HDAC1 (0.51) | HDAC4MEF2DHDAC1HDAC3HDAC2 | |
| SCHEMBL4224028 | 0.88 | UTS2R (0.43) | HDAC4HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL2384389 | 0.87 | HDAC1 (0.47) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL2386015 | 0.87 | HDAC3 (0.43) | HDAC4HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL3234631 | 0.86 | NAMPT (0.42) | NAMPTUTS2R | |
| SCHEMBL4225186 | 0.86 | HDAC3 (0.46) | HDAC4HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL3230138 | 0.86 | UTS2R (0.47) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL3229763 | 0.86 | HDAC1 (0.47) | HDAC1HDAC3HDAC2HDAC8HDAC10 | |
| SCHEMBL2384770 | 0.86 | UTS2R (0.54) | HDAC4HDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133339-A1 | NOVEL (2-AMINOPHENYL)PYRIDINECARBOXAMIDE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-12-16 | — | — | EP | disclosed |