Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4911281 | 0.91 | MAPT (0.66) | MAPTTP53ALDH1A1HPGDGAA | |
| SCHEMBL4229143 | 0.91 | TP53 (0.66) | MAPTTP53ALDH1A1HPGDGAA | |
| SCHEMBL4903742 | 0.89 | MAPT (0.69) | MAPTTP53ALDH1A1HPGDGAA | |
| SCHEMBL4911374 | 0.85 | TP53 (0.74) | MAPTTP53ALDH1A1HPGDGAA | |
| SCHEMBL4232725 | 0.85 | MAPT (0.62) | MAPTTP53ALDH1A1HPGDGAA | |
| SCHEMBL4906330 | 0.85 | TP53 (0.74) | MAPTTP53ALDH1A1HPGDGAA | |
| SCHEMBL4909380 | 0.84 | TP53 (0.73) | MAPTTP53ALDH1A1HPGDGAA | |
| SCHEMBL4907886 | 0.84 | MAPT (0.73) | MAPTTP53ALDH1A1HPGDGAA | |
| SCHEMBL4915791 | 0.84 | MAPT (0.73) | MAPTTP53ALDH1A1HPGDGAA | |
| SCHEMBL4229261 | 0.83 | MAPT (0.59) | MAPTTP53ALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090062360-A1 | Compounds Which Inhibit the Glycine Transporter and Uses Thereof | GLAXO GROUP LIMITED (GB) | 2009-03-05 | — | — | US | claimed |
| US-20090062360-A1 | Compounds Which Inhibit the Glycine Transporter and Uses Thereof | GLAXO GROUP LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
| US-20090062360-A1 | Compounds Which Inhibit the Glycine Transporter and Uses Thereof | GLAXO GROUP LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
| US-20090062360-A1 | Compounds Which Inhibit the Glycine Transporter and Uses Thereof | GLAXO GROUP LIMITED (GB) | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062360-A1 | Compounds Which Inhibit the Glycine Transporter and Uses Thereof | SLC18A2, SLC1A2, SLC1A1 | MAPT 221/4885TP53 3543/4885ALDH1A1 974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.